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Imaging Tools for Chemical Biology
Chemical Biology
Imaging Tools for Chemical Biology
Edited by
Lei Feng
Lei Feng
Dalian Medical University, China
  https://orcid.org/0000-0003-2377-0190
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Tony D James
Tony D James
University of Bath, UK
  https://orcid.org/0000-0002-4095-2191
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Volume
24
DOI:
https://doi.org/10.1039/9781837673117
Hardback ISBN:
978-1-83767-115-1
PDF ISBN:
978-1-83767-311-7
EPUB ISBN:
978-1-83767-312-4
Special Collection: 2024 eBook Collection
No. of Pages:
380
Publication date:
31 Oct 2024
Book Chapter

Chapter 2: NIR-II Bioimaging

By
P. Li
P. Li
aCollege of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Biomedical Sciences, Shandong Normal University, Jinan 250014, P. R. China [email protected]
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;
B. Tang
B. Tang
aCollege of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Institute of Biomedical Sciences, Shandong Normal University, Jinan 250014, P. R. China
bLaoshan Laboratory, 168 Wenhai Middle Rd, Aoshanwei Jimo, Qingdao 266237, Shandong, P. R. China
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Doi:
https://doi.org/10.1039/9781837673117-00035
Page range:
35 - 47

Fluorescent probes that emit in the second near-infrared region (NIR-II, 1000–1700 nm) possess unique advantages, including low photodamage and deep penetration into biological samples. Notably, NIR-II optical imaging can achieve tissue penetration as deep as 5–20 mm, which is critical for biomedical sensing and clinical applications. Many researchers have developed NIR-II dyes to meet the needs of modern biomedicine. This chapter will review the NIR-II fluorescent probes for biomolecules and for therapeutic applications.

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