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Blood purification, including hemodialysis, plasma exchange, blood perfusion, and so on, is an effective strategy for the symptomatic treatment of many complex blood-related disorders that are refractory to conventional therapies. Since George Haas first applied dialysis to humans in 1926, modern blood purification therapy has a history of nearly a century. Nowadays, blood dialysis provides life support for millions of patients with renal failure every year, generating enormous social and economic benefits. According to data released by Fresenius Medical Care, the global hemodialysis market size reached $94.43 billion in 2022 and is expected to reach $158.04 billion by 2030.

Blood purification materials consist of membrane materials and adsorption materials, mainly composed of polymer products. Different fields of application have different requirements regarding their basic composition, structure, and performance. Blood purification materials with high performance are the foundation of blood purification treatment, and progress with these materials constantly promotes the emergence of various new treatment methods.

Some useful monographs have been published in the field of blood purification treatment, but most of them discussed blood purification techniques or devices specifically. This book is focused on blood purification materials. First, the requirements for the blood compatibility of blood purification materials are discussed. Then, from the perspectives of membranes and adsorption materials, the classification, preparation, and modification methods of blood purification materials, and their application in different fields of blood purification, are described.

The book is divided into six parts with a total of 14 chapters. The first part (Chapter 1) provides an introduction, while the second part (Chapters 2 and 3) discusses the requirements and challenges for blood purification materials. The third (Chapters 4–8) and fourth parts (Chapters 9–11) discuss membrane materials and adsorption materials, respectively, and the fifth part (Chapters 12 and 13) mainly describes the processing and assembly of blood purification materials. The final part (Chapter 14) provides a brief outlook on future development trends in blood purification materials.

It is my privilege to bring together the work of internationally recognized experts engaged in research on blood purification materials. During the preparation of this book, we received strong support from the contributing authors and their institutions, and I want to thank all of them for their good work and patience during the completion of this project. I believe that their expertise and knowledge have ensured the quality of this book, and I sincerely hope that readers will enjoy and benefit from reading their informative chapters.

Changsheng Zhao

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