Chapter 8: Biosensors for the Determination of Toxic Phenolic Compounds Present in Cosmetics

The cosmetic industry has witnessed significant growth in recent years, accompanied by increasing concerns regarding the safety of cosmetic ingredients, particularly toxic phenolic compounds. These compounds, commonly used in cosmetics for their preservative, fragrance, or antioxidant properties, pose potential health risks, including endocrine disruption, allergic reactions, and carcinogenicity. In response to these concerns, the development of biosensors tailored for the determination of toxic phenolic compounds in cosmetics has emerged as a critical area of research and innovation. Biosensors offer a promising solution for rapid, sensitive, and selective detection of these compounds, enabling timely identification and monitoring of hazardous ingredients in cosmetic formulations. This chapter explores the principles, mechanisms, and analytical performance of biosensors designed for detecting toxic phenolic compounds in cosmetics. It discusses the various types of biosensors suitable for this application, highlighting their sensitivity, selectivity, and potential for on-site analysis. Furthermore, it examines opportunities for improvement and innovation in biosensor technology, addressing challenges and outlining a path toward enhanced safety and transparency in the cosmetic industry. Through a comprehensive analysis of biosensors for the determination of toxic phenolic compounds in cosmetics, this chapter aims to provide valuable insights for researchers, industry professionals, and regulatory authorities, ultimately contributing to the advancement of cosmetic safety assessment and consumer protection.