Chapter 5: Potentiometric Devices for Biomarkers
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Published:20 Dec 2024
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Special Collection: 2024 eBook CollectionSeries: Detection Science Series
A. Arora and K. K. Yadav, in Sensing Materials and Devices for Biomarkers, ed. V. Mutreja, D. Kathuria, S. Sareen, and J. Park, Royal Society of Chemistry, 2024, vol. 28, ch. 5, pp. 146-165.
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Potentiometric biosensors facilitate the detection of numerous biologically important substances and aid in the early diagnosis of various health issues. These sensors are crucial components of portable analytical devices used for monitoring biomarkers in the body. They operate using ion-sensitive membranes that create a potential gradient due to differences in the concentration and activity of various ions and antibodies, which are tracked to detect harmful health conditions. Additionally, potentiometric sensors can be integrated with other analytical methods to develop diagnostic tools for the rapid and precise identification of biomarkers, such as those used in cancer diagnosis and the detection of chloride ions in sweat. This chapter discusses the fundamental principles and classification of potentiometric biosensing devices. It also highlights various potentiometric biosensor devices that serve as reliable platforms for biomarker testing.