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Biomaterials Science Series
Ophthalmic BiomaterialsCheck Access
Edited by
https://orcid.org/0000-0002-7524-2798
Heather Sheardown
Heather Sheardown
McMaster University, Canada
Search for other works by this author on:
Volume
20
Hardback ISBN:
978-1-83916-441-5
PDF ISBN:
978-1-83916-977-9
EPUB ISBN:
978-1-83916-978-6
Special Collection:
2025 eBook Collection
Series:
Biomaterials Science Series
No. of Pages:
510
Publication date:
11 Jun 2025
About this book
Advances in technology have rapidly changed the way we treat ophthalmic diseases, especially with the development of new biomaterials used as prosthetics, for drug delivery devices, or to regenerate tissue.
Bridging the gap between biomaterials scientists and ophthalmologists, this book includes overviews of devices and cutting-edge research on current and future strategies to treat acute and chronic diseases in the eye.
Edited by leaders in the field, the book provides perspectives for both biomaterials scientists and ophthalmologists. Biomaterials scientists are given a background to the challenges in ophthalmology that advanced materials could solve. Ophthalmologists are provided a background on materials to enable them to better understand the devices they are using and their advantages and challenges. All readers are provided with a critical review of the current and future state of devices that are being used or are under development in devices, regenerative medicine, and drug delivery.
This book is for those working in biomaterials science, biomedical engineering, chemical engineering, and clinicians specialising in ophthalmology, as well as those working in polymer science-based medical technologies.
Ophthalmic Biomaterials, Royal Society of Chemistry, 2025.
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Digital access
$290.00
Print format
Ophthalmic Biomaterials
$290.00
Table of contents
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Chapter 1: Anatomy and Physiology of the Eyep1-12ByLindsay Sheardown;Lindsay SheardownMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, CanadaSearch for other works by this author on:Emily Anne Hicks;Emily Anne HicksMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, CanadaSearch for other works by this author on:Heather SheardownHeather SheardownMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, Canada[email protected]Search for other works by this author on:
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Chapter 2: Contact Lenses: Current Designs and New Strategiesp13-47ByNicole Carnt;Nicole CarntSchool of Optometry and Vision Science, UNSW, Sydney, Australia[email protected]Search for other works by this author on:Adam Samuels;Adam SamuelsSchool of Optometry and Vision Science, UNSW, Sydney, AustraliaSearch for other works by this author on:S. L. Stephanie Yeo;S. L. Stephanie YeoSchool of Optometry and Vision Science, UNSW, Sydney, AustraliaSearch for other works by this author on:Fiona StapletonFiona StapletonSchool of Optometry and Vision Science, UNSW, Sydney, AustraliaSearch for other works by this author on:
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Chapter 3: Intraocular Lensesp48-71ByS. Karim;S. KarimQueen’s University, Kingston, ON, CanadaSearch for other works by this author on:C. A. Rayner;C. A. RaynerQueen’s University, Kingston, ON, CanadaSearch for other works by this author on:L. A. WellsL. A. WellsQueen’s University, Kingston, ON, Canada[email protected]Search for other works by this author on:
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Chapter 4: Vitreous Substitutesp72-96ByAdam Forman;Adam FormanaDepartment of Chemical Engineering & Applied Chemistry, University of Toronto, 200 College St, Toronto, ON M5S 3E5, CanadabInstitute of Biomedical Engineering, University of Toronto, 170 College St, Toronto, ON M5S 3E3, CanadacTerrence Donnelly Centre for Cellular & Biomolecular Research, University of Toronto, 160 College St, Toronto, ON M5S 3E1, CanadaSearch for other works by this author on:Alexander E. G. Baker;Alexander E. G. BakerdDepartment of Chemistry, Dalhousie University, 6243 Alumni Crescent, Halifax, NS B3H 4R2, CanadaSearch for other works by this author on:Molly S. ShoichetMolly S. ShoichetaDepartment of Chemical Engineering & Applied Chemistry, University of Toronto, 200 College St, Toronto, ON M5S 3E5, CanadabInstitute of Biomedical Engineering, University of Toronto, 170 College St, Toronto, ON M5S 3E3, CanadacTerrence Donnelly Centre for Cellular & Biomolecular Research, University of Toronto, 160 College St, Toronto, ON M5S 3E1, Canada [email protected]Search for other works by this author on:
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Chapter 5: Emerging Biomaterials for Retinal Implantsp97-149ByM. L. Italiano;M. L. ItalianoaGraduate School of Biomedical Engineering, UNSW Sydney, AustraliabTyree Foundation Institute of Health Engineering (iHealthE), UNSW Sydney, AustraliaSearch for other works by this author on:T. Guo;T. GuoaGraduate School of Biomedical Engineering, UNSW Sydney, AustraliaSearch for other works by this author on:D. Tsai;D. TsaiaGraduate School of Biomedical Engineering, UNSW Sydney, AustraliacSchool of Electrical Engineering and Telecommunications, UNSW Sydney, AustraliaSearch for other works by this author on:N. H. Lovell;N. H. LovellaGraduate School of Biomedical Engineering, UNSW Sydney, AustraliabTyree Foundation Institute of Health Engineering (iHealthE), UNSW Sydney, AustraliaSearch for other works by this author on:M. N. ShivdasaniM. N. ShivdasaniaGraduate School of Biomedical Engineering, UNSW Sydney, AustraliabTyree Foundation Institute of Health Engineering (iHealthE), UNSW Sydney, Australia[email protected]Search for other works by this author on:
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Chapter 6: Orbital Implants After Enucleation and Eviscerationp150-172ByMeydan Ben-Ishai;Meydan Ben-IshaiaDepartment of Ophthalmology, Rabin Medical Center, Petach Tikva, IsraelSearch for other works by this author on:Raman Malhotra;Raman MalhotrabCorneoplastic Unit, Queen Victoria Hospital NHS Trust, East Grinstead, West Sussex RH19 3DZ, UKSearch for other works by this author on:Bhupendra C. K. PatelBhupendra C. K. PatelcDepartment of Facial Cosmetic & Reconstructive Surgery, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA[email protected]Search for other works by this author on:
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Chapter 7: Use of Modern Biomaterials in Ocular and Facial Prosthesesp173-189ByPaul Tanner;Paul TanneraDepartment of Facial Prosthetics, Huntsman Cancer Hospital, University of Utah, Salt Lake City, Utah 84112, USASearch for other works by this author on:Bhupendra C. K. PatelBhupendra C. K. Patelb Department of Facial Cosmetic & Reconstructive Surgery, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA[email protected]Search for other works by this author on:
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Chapter 8: Strategies to Replace and Regenerate the Cornea and Other Tissues in the Anterior Segmentp190-255ByCristina Bostan;Cristina BostanaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadabDepartment of Ophthalmology, Université de Montréal, Montreal, Quebec, CanadacCentre universitaire d’ophtalmologie de l’Université de Montréal at the Maisonneuve-Rosemont Hospital, Canada [email protected]†Search for other works by this author on:Emilio I. Alarcón;Emilio I. AlarcóndBioengineering and Therapeutic Solutions (BEaTS) Program, University of Ottawa Heart Institute, Ottawa, Ontario, CanadaeDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, Canada[email protected]†Search for other works by this author on:Mehrshad Hanafimosalman;Mehrshad HanafimosalmanaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadaSearch for other works by this author on:Christian Tebid Tebid;Christian Tebid TebidaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadafDepartment of Medicine, Université de Montréal, Montreal, Quebec, CanadaSearch for other works by this author on:Anas Abu Dieh;Anas Abu DiehaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadaSearch for other works by this author on:Patrick Bedford;Patrick BedfordgweCANreg Consulting Group Inc., Waterdown, Ontario, CanadaSearch for other works by this author on:Astha Chandra;Astha ChandraaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadadBioengineering and Therapeutic Solutions (BEaTS) Program, University of Ottawa Heart Institute, Ottawa, Ontario, CanadaSearch for other works by this author on:Darlene Dartt;Darlene DartthSchepens Eye Research Institute, Harvard Medical School, Boston, MA, USASearch for other works by this author on:Vibhuti P. Dave;Vibhuti P. DaveaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadaiDepartment of Microbiology, Infectology and Immunology, Université de Montréal, Montreal, Quebec, CanadaSearch for other works by this author on:Isabelle Brunette;Isabelle BrunetteaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadabDepartment of Ophthalmology, Université de Montréal, Montreal, Quebec, CanadaSearch for other works by this author on:Marie-Claude Robert;Marie-Claude RobertaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadabDepartment of Ophthalmology, Université de Montréal, Montreal, Quebec, CanadaSearch for other works by this author on:Mark Lesk;Mark LeskaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadabDepartment of Ophthalmology, Université de Montréal, Montreal, Quebec, CanadaSearch for other works by this author on:Denis Claude Roy;Denis Claude RoyaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadafDepartment of Medicine, Université de Montréal, Montreal, Quebec, CanadaSearch for other works by this author on:Brenda Truong;Brenda TruongdBioengineering and Therapeutic Solutions (BEaTS) Program, University of Ottawa Heart Institute, Ottawa, Ontario, CanadaeDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaSearch for other works by this author on:Irene Guzman-Soto;Irene Guzman-SotodBioengineering and Therapeutic Solutions (BEaTS) Program, University of Ottawa Heart Institute, Ottawa, Ontario, CanadaeDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadaSearch for other works by this author on:May GriffithMay GriffithaMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadabDepartment of Ophthalmology, Université de Montréal, Montreal, Quebec, CanadaeDepartment of Biochemistry, Microbiology, and Immunology, University of Ottawa, Ottawa, Ontario, CanadajInstitute of Biomedical Engineering, Université de Montréal, Montreal, Quebec, Canada[email protected]Search for other works by this author on:
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Chapter 9: Biomaterials in Retinal Regenerationp256-286ByE. A. Hicks;E. A. HicksMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, Ontario, CanadaSearch for other works by this author on:A. Monteiro;A. MonteiroMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, Ontario, CanadaSearch for other works by this author on:N. Tran;N. TranMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, Ontario, CanadaSearch for other works by this author on:L. Sheardown;L. SheardownMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, Ontario, CanadaSearch for other works by this author on:H. SheardownH. SheardownMcMaster University, Department of Chemical Engineering, 1280 Main St W, L8S 4L8, Hamilton, Ontario, Canada[email protected]Search for other works by this author on:
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Chapter 10: Tarsal Plate Substitutes in Modern Reconstructive Plastic Surgery of Eyelidsp287-310ByChristina Lim;Christina LimaCorneoplastic Unit, Queen Victoria Hospital NHS Trust, East Grinstead, West Sussex RH19 3DZ, UKSearch for other works by this author on:Raman Malhotra;Raman MalhotraaCorneoplastic Unit, Queen Victoria Hospital NHS Trust, East Grinstead, West Sussex RH19 3DZ, UKSearch for other works by this author on:Bhupendra C. K. PatelBhupendra C. K. PatelbDepartment of Facial Cosmetic & Reconstructive Surgery, Moran Eye Center, University of Utah, Salt Lake City, Utah 84132, USA[email protected]Search for other works by this author on:
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Chapter 11: Anterior Segment Drug Deliveryp311-348ByWilliam Ngo;William NgoaSchool of Optometry & Vision Science, University of Waterloo, 200 University Avenue W, Waterloo, Ontario, N2L 3G1, CanadaSearch for other works by this author on:Chau Minh-Phan;Chau Minh-PhanbCentre for Ocular Research and Education, School of Optometry & Vision Science, University of Waterloo, 200 University Avenue W, Waterloo, Ontario, N2L 3G1, CanadaSearch for other works by this author on:Alex HuiAlex HuibCentre for Ocular Research and Education, School of Optometry & Vision Science, University of Waterloo, 200 University Avenue W, Waterloo, Ontario, N2L 3G1, CanadacSchool of Optometry and Vision Science, UNSW Sydney, Sydney, NSW, 2052, Australia[email protected]Search for other works by this author on:
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Chapter 12: Protecting Sight: Advances in Drug Delivery to the Posterior Segment to Combat Vision Lossp349-398ByM. M. Allyn;M. M. AllynaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 W Woodruff Ave, Columbus, OH 43210, USASearch for other works by this author on:K. E. Swindle-ReillyK. E. Swindle-ReillyaWilliam G. Lowrie Department of Chemical and Biomolecular Engineering, The Ohio State University, 151 W Woodruff Ave, Columbus, OH 43210, USAbDepartment of Biomedical Engineering, The Ohio State University, 140 W 19th Ave, Columbus, OH 43210, USAcDepartment of Ophthalmology and Visual Sciences, The Ohio State University, 915 Olentangy River Rd, 43212, Columbus, OH, USA[email protected]Search for other works by this author on:
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Chapter 13: Microneedle Approaches to Ocular Drug Deliveryp399-418ByAaron R. J. Hutton;Aaron R. J. HuttonSchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, BT9 7BL, UKSearch for other works by this author on:Yu Wu;Yu WuSchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, BT9 7BL, UKSearch for other works by this author on:Ke Peng;Ke PengSchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, BT9 7BL, UKSearch for other works by this author on:Thakur Raghu Raj Singh;Thakur Raghu Raj SinghSchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, BT9 7BL, UKSearch for other works by this author on:Ryan F. DonnellyRyan F. DonnellySchool of Pharmacy, Queen’s University Belfast, 97 Lisburn Road, BT9 7BL, UK[email protected]Search for other works by this author on:
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Chapter 14: Smart Materials in Ophthalmic Applicationsp419-443ByJ. Jimenez;J. JimenezaDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, 15213, USASearch for other works by this author on:E. Phelps;E. PhelpsbDepartment of Neuroscience, University of Pittsburgh, Pittsburgh, PA, 15213, USASearch for other works by this author on:M. V. DiLeoM. V. DiLeoaDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, 15213, USAcDepartment of Ophthalmology, University of Pittsburgh, Pittsburgh, PA, 15213, USAdDepartment of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA, 15213, USAeClinical and Translational Science Institute, Pittsburgh, PA 15213, USAfMcGowan Institute for Regenerative Medicine, Pittsburgh, PA 15213, USA[email protected]Search for other works by this author on:
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Chapter 15: Negotiating the Regulatory Pathwayp444-475ByPatrick Bedford;Patrick BedfordaweCANreg Consulting Group Inc., Waterdown, Ontario, Canada†Search for other works by this author on:Cristina Bostan;Cristina BostanbMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadacDepartment of Ophthalmology, Université de Montréal, Montreal, Quebec, CanadadCentre universitaire d’ophtalmologie de l’Université de Montréal at the Maisonneuve Rosemont Hospital, Montreal, Canada†Search for other works by this author on:May GriffithMay GriffithbMaisonneuve-Rosemont Hospital Research Centre, Montreal, Quebec, CanadaeInstitute of Biomedical Engineering, Université de Montréal, Montreal, Quebec, Canada[email protected]Search for other works by this author on:
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