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Biomaterials Science Series
Immunomodulatory Biomaterials: Definition, Design, and ApplicationCheck Access
Edited by
Weiwei Wang;
Weiwei Wang
College of Life Sciences, Nankai University, China
https://orcid.org/0000-0003-0333-0868
Search for other works by this author on:
Zujian Feng;
Zujian Feng
Chinese Academy of Medical Sciences & Peking Union Medical College, China
Search for other works by this author on:
Pingsheng Huang
Pingsheng Huang
Chinese Academy of Medical Sciences & Peking Union Medical College, China
Search for other works by this author on:
Volume
21
Hardback ISBN:
978-1-83767-169-4
EPUB ISBN:
978-1-83767-574-6
PDF ISBN:
978-1-83767-573-9
Special Collection:
2025 eBook Collection
Series:
Biomaterials Science Series
No. of Pages:
306
Publication date:
13 Jun 2025
About this book
The ability to modulate the body's immune system can greatly assist the treatment of diseases and repair of injured tissues. Immunomodulatory biomaterials can promote adaptive immunity, without the need for drugs, cytokines or cell therapies. Their design can be targeted towards specific applications, including cancer and inflammatory disease.
Exploring the latest research, the authors present their philosophy for the design of immunomodulatory biomaterials and aim to close the gap between materials scientists, engineers, and biologists. The book includes an overview of the immune system, the immune response biomaterials may create, and various design strategies across a range of biomedical contexts. The book concludes with an outlook on the future of this topic and how it will translate to the clinic.
Immunomodulatory Biomaterials: Definition, Design, and Application, Royal Society of Chemistry, 2025.
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Digital access
$250.00
Print format
Immunomodulatory Biomaterials
$250.00
Table of contents
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Chapter 1: Introductionp1-3ByWeiwei WangWeiwei WangaTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinabCollege of Life Sciences, Nankai University, Tianjin 300071, China[email protected]; [email protected]Search for other works by this author on:
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Chapter 2: Overview of the Body’s Immune Systemp4-6ByWeiwei WangWeiwei WangaTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinabCollege of Life Sciences, Nankai University, Tianjin 300071, China[email protected]Search for other works by this author on:
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Chapter 3: The Immune Response Induced by Biomaterial Implantationp7-23ByQinghua Li;Qinghua LiTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinaSearch for other works by this author on:Pingsheng HuangPingsheng HuangTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 4: The Design and Manipulation Principles of Immunomodulatory Biomaterialsp24-97ByRui Gao;Rui GaoTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinaSearch for other works by this author on:Yushan Zhang;Yushan ZhangTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinaSearch for other works by this author on:Yu Gao;Yu GaoTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinaSearch for other works by this author on:Zujian FengZujian FengTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 5: The Fundamentals of Cancer Immunityp98-109ByHaixue Jia;Haixue JiaChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, ChinaSearch for other works by this author on:Lijun Yang;Lijun YangChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, China[email protected]Search for other works by this author on:Jianfeng LiuJianfeng LiuChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 6: Biomaterials-based Vaccine for Cancer Immunotherapyp110-123ByZhongyan Wang;Zhongyan WangChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, ChinaSearch for other works by this author on:Chunhua RenChunhua RenChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 7: Biomaterials-enhanced Adoptive Cell Transfer (ACT) Therapyp124-147ByYumin Zhang;Yumin ZhangaChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, ChinaSearch for other works by this author on:Baixue Fu;Baixue FuaChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, ChinabNankai University, Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Tianjin 300071, ChinaSearch for other works by this author on:Yongjian Wang;Yongjian WangbNankai University, Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Tianjin 300071, ChinaSearch for other works by this author on:Cuihong YangCuihong YangaChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 8: Antigenic Peptide Hydrogels for Cancer Vaccinationp148-158ByHuijuan Song;Huijuan SongChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, ChinaSearch for other works by this author on:Qiang LiuQiang LiuChinese Academy of Medical Sciences & Peking Union Medical College, State Key Laboratory of Advanced Medical Materials and Devices, Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Key Laboratory of Radiopharmacokinetics for Innovative Drugs, Tianjin Institutes of Health Science, Institute of Radiation Medicine, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 9: Gene Delivery for Cancer Immunotherapyp159-183ByChangrong Wang;Changrong WangDepartment of Biotechnology, School of Life Science and Technology, Xidian University and Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi’an 710126, ChinaSearch for other works by this author on:Hongzhang DengHongzhang DengDepartment of Biotechnology, School of Life Science and Technology, Xidian University and Engineering Research Center of Molecular and Neuro Imaging, Ministry of Education, Xi’an 710126, China[email protected]Search for other works by this author on:
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Chapter 10: Immunomodulatory Biomaterials for Treating Autoimmune Diseasesp184-201ByGaona Shi;Gaona ShiaState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, ChinaSearch for other works by this author on:Xuefeng Gao;Xuefeng GaoaState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, ChinaSearch for other works by this author on:Junjie Yang;Junjie YangaState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, ChinaSearch for other works by this author on:Weiwei Wang;Weiwei WangbState Key Laboratory of Advanced Medical Materials and Devices, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China[email protected]Search for other works by this author on:Tiantai ZhangTiantai ZhangaState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China[email protected]Search for other works by this author on:
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Chapter 11: Immunomodulatory Biomaterials for Cardiac Repairp202-222ByJingrong Wang;Jingrong WangTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinaSearch for other works by this author on:Zujian FengZujian FengTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 12: Bone Repair Using Immunomodulatory Biomaterialsp223-249ByJumin Yang;Jumin YangThe First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, ChinaSearch for other works by this author on:Yaping WangYaping WangThe First Affiliated Hospital of Zhengzhou University, Zhengzhou 450000, China[email protected]Search for other works by this author on:
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Chapter 13: Healing Chronic Wounds with Immunomodulatory Biomaterialsp250-264ByQi Su;Qi SuTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, ChinaSearch for other works by this author on:Weiwei WangWeiwei WangTianjin Key Laboratory of Biomaterial Research, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China[email protected]Search for other works by this author on:
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Chapter 14: Immunomodulatory Biomaterials for Spinal Cord Injuryp265-273ByPengxiang YangPengxiang YangKey Laboratory of Neuroregeneration of Jiangsu Province and Ministry of Education, Co-Innovation Center of Neuroregeneration, NMPA Key Laboratory for Research and Evaluation of Tissue Engineering Technology Products, Nantong University, 226001, Nantong, China[email protected]Search for other works by this author on:
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Chapter 15: Outlookp274-279ByWeiwei WangWeiwei WangTianjin Key Laboratory of Biomaterial Research Institute of Biomedical Engineering, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300192, China[email protected]Search for other works by this author on:
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