Chapter 3: Immunologically-based Methods for Detecting Masked Mycotoxins
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Published:05 Nov 2015
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Series: Issues in Toxicology
C. M. Maragos, in Masked Mycotoxins in Food: Formation, Occurrence and Toxicological Relevance, ed. C. Dall'Asta and F. Berthiller, The Royal Society of Chemistry, 2015, ch. 3, pp. 32-49.
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Masked mycotoxins are plant metabolites of known mycotoxins. Immunoassays can be developed with either broad cross-reaction to mycotoxin congeners or with high selectivity for a particular toxin. The result is that certain assays are able to detect masked mycotoxins along with the free (or ‘parent’) form, while others do not. This chapter summarises the ability of reported immunoassays, commercial or otherwise, to detect or to isolate masked mycotoxins. In addition, the basis for why certain immunoassays recognise masked mycotoxins, while others do not, is explored.
