Advances in Biological Solid-State NMR: Proteins and Membrane-Active Peptides
The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid-state NMR. This technique can address fascinating problems in structural biology, including the arrangement of supramolecular complexes and fibril formation in relation to molecular folding, misfolding and aggregation.
Advances in Biological Solid-State NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid-state NMR to studies of membrane interactions and molecular motions. A much needed discussion of membrane systems is detailed alongside important developments in in situ analysis.
Topics include applications to biological membranes, membrane active peptides, membrane proteins, protein assemblies and in-cell NMR. This exposition of an invaluable technique will interest those working in a range of related spectroscopic and biological fields. A basic introduction invites those interested to familiarise themselves with the basic mathematical and conceptual foundations of solid-state NMR. A thorough and comprehensive discussion of this promising technique follows, which is essential reading for those working or studying at postgraduate level in this exciting field.
Advances in Biological Solid-State NMR: Proteins and Membrane-Active Peptides, The Royal Society of Chemistry, 2014.
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CHAPTER 1: Introduction to Biological Solid-State NMRp1-17ByM. Weingarth;M. WeingarthBijvoet Center for Biomolecular Research, Faculty of Science, Utrecht UniversityPadualaan 83584 CH UtrechtThe Netherlands[email protected]Search for other works by this author on:M. BaldusM. BaldusBijvoet Center for Biomolecular Research, Faculty of Science, Utrecht UniversityPadualaan 83584 CH UtrechtThe Netherlands[email protected]Search for other works by this author on:
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CHAPTER 2: Combining NMR Spectroscopic Measurements and Molecular Dynamics Simulations to Determine the Orientation of Amphipathic Peptides in Lipid Bilayersp18-35ByB. Scott Perrin Jr.;B. Scott Perrin Jr.Laboratory of Computational Biology, National Heart, Lung and Blood Institute, National Institutes of HealthBethesda, MD20892USASearch for other works by this author on:Richard W. Pastor;Richard W. PastorLaboratory of Computational Biology, National Heart, Lung and Blood Institute, National Institutes of HealthBethesda, MD20892USASearch for other works by this author on:Myriam CottenMyriam CottenSearch for other works by this author on:
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CHAPTER 3: 13C–13C Distance Measurements by Polarization Transfer Matrix Analysis of 13C Spin Diffusion in a Uniformly 13C-Labeled Molecular Complex under Magic Angle Spinningp36-52ByToshimichi FujiwaraToshimichi FujiwaraSearch for other works by this author on:
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CHAPTER 4: Demonstration of the Equivalence of Solid-State NMR Orientational Constraints from Magnetic and Rotational Alignment of the Coat Protein in a Filamentous Bacteriophagep53-70ByBibhuti B. DasBibhuti B. DasSearch for other works by this author on:
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CHAPTER 5: Membrane Protein Interactionsp71-97ByJames A. Jarvis;James A. JarvisCentre for Biological Sciences/Institute for Life Sciences, University of SouthamptonHighfield CampusSouthamptonSO17 1BJUK[email protected]Search for other works by this author on:Philip T. F. WilliamsonPhilip T. F. WilliamsonCentre for Biological Sciences/Institute for Life Sciences, University of SouthamptonHighfield CampusSouthamptonSO17 1BJUK[email protected]Search for other works by this author on:
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CHAPTER 6: Magnetic Liposomes and Bicelles: New Tools for Membrane-Peptide Structural Studiesp98-112ByErick J. Dufourc;Erick J. DufourcInstitute of Chemistry & Biology of Membranes & Nanoobjects, UMR 5248, Université Bordeaux, CNRS, Institut Polytechnique BordeauxAllée Geoffroy Saint Hilaire33600PessacFranceSearch for other works by this author on:Nicole Harmouche;Nicole HarmoucheInstitute of Chemistry & Biology of Membranes & Nanoobjects, UMR 5248, Université Bordeaux, CNRS, Institut Polytechnique BordeauxAllée Geoffroy Saint Hilaire33600PessacFranceSearch for other works by this author on:Cécile Loudet-Courrèges;Cécile Loudet-CourrègesInstitute of Chemistry & Biology of Membranes & Nanoobjects, UMR 5248, Université Bordeaux, CNRS, Institut Polytechnique BordeauxAllée Geoffroy Saint Hilaire33600PessacFranceSearch for other works by this author on:Reiko Oda;Reiko OdaInstitute of Chemistry & Biology of Membranes & Nanoobjects, UMR 5248, Université Bordeaux, CNRS, Institut Polytechnique BordeauxAllée Geoffroy Saint Hilaire33600PessacFranceSearch for other works by this author on:Anna Diller;Anna DillerInstitute of Experimental Genetics/Institute of Structural BiologyHelmholtz Zentrum, MünchenGermany[email protected]Search for other works by this author on:Benoit Odaert;Benoit OdaertInstitute of Chemistry & Biology of Membranes & Nanoobjects, UMR 5248, Université Bordeaux, CNRS, Institut Polytechnique BordeauxAllée Geoffroy Saint Hilaire33600PessacFranceSearch for other works by this author on:Axelle Grélard;Axelle GrélardInstitute of Chemistry & Biology of Membranes & Nanoobjects, UMR 5248, Université Bordeaux, CNRS, Institut Polytechnique BordeauxAllée Geoffroy Saint Hilaire33600PessacFranceSearch for other works by this author on:Sébastien BuchouxSébastien BuchouxEnzyme & Cell Engineering (GEC), UMR6022, Université Picardie Jules Verne, CNRSAmiensFranceSearch for other works by this author on:
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CHAPTER 7: Membranes and Their Lipids: A Molecular Insight into Their Organization and Functionp113-132ByMartin Lidman;Martin LidmanDepartment of Chemistry, Umeå University90187UmeåSwedenSearch for other works by this author on:Gerhard GröbnerGerhard GröbnerDepartment of Chemistry, Umeå University90187UmeåSwedenSearch for other works by this author on:
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CHAPTER 8: Structural Studies of Small Bioactive Compounds Interacting with Membranes and Proteinsp133-161ByShigeru Matsuoka;Shigeru MatsuokaJST·ERATO Lipid Active Structure Project, Project Research Centre for Fundamental Science, Osaka University, Department of Chemistry, Graduate School of Science, Osaka University1–1 MachikaneyamaToyonaka, Osaka560–0043Japan[email protected]Search for other works by this author on:Michio MurataMichio MurataJST·ERATO Lipid Active Structure Project, Project Research Centre for Fundamental Science, Osaka University, Department of Chemistry, Graduate School of Science, Osaka University1–1 MachikaneyamaToyonaka, Osaka560–0043Japan[email protected]Search for other works by this author on:
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CHAPTER 9: Lipopolysaccharide Induces Raft Domain Expansion in a Cholesterol-Containing Membranep162-179ByKaoru Nomura;Kaoru NomuraSuntory Institute for Bioorganic Research1-1-1 WakayamadaiShimamoto-Cho, Mishima-Gun, Osaka618–8503Japan[email protected]Search for other works by this author on:Shoichi KusumotoShoichi KusumotoSuntory Institute for Bioorganic Research1-1-1 WakayamadaiShimamoto-Cho, Mishima-Gun, Osaka618–8503Japan[email protected]Search for other works by this author on:
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CHAPTER 10: Deuterium NMR of Mixed Lipid Membranesp180-199BySherry S. W. Leung;Sherry S. W. LeungDepartment of Physics, Simon Fraser UniversityBritish ColumbiaCanadaSearch for other works by this author on:Jenifer ThewaltJenifer ThewaltDepartment of Physics, Simon Fraser UniversityBritish ColumbiaCanadaDepartment of Molecular Biology and Biochemistry, Simon Fraser UniversityBritish ColumbiaCanadaDepartment of Dermatology and Skin Science, University of British ColumbiaBritish ColumbiaCanada[email protected]Search for other works by this author on:
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CHAPTER 11: Membrane Interactions of Amphiphilic Peptides with Antimicrobial Potential: A Solid-State NMR Studyp200-213ByMatthieu Fillion;Matthieu FillionDepartment of Chemistry, Regroupement québécois de recherche sur la fonction, la structure et l’ingénierie des protéines (PROTEO), Centre de recherche sur les matériaux avancés (CERMA), Centre québécois sur les matériaux fonctionnels (CQMF), Université LavalQuébec, QCCanada, G1V 0A6Search for other works by this author on:Michèle AugerMichèle AugerDepartment of Chemistry, Regroupement québécois de recherche sur la fonction, la structure et l’ingénierie des protéines (PROTEO), Centre de recherche sur les matériaux avancés (CERMA), Centre québécois sur les matériaux fonctionnels (CQMF), Université LavalQuébec, QCCanada, G1V 0A6Search for other works by this author on:
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CHAPTER 12: Investigations of the Structure, Topology and Dynamics of Membrane-Associated Polypeptides by Solid-State NMR Spectroscopyp214-234ByEvgeniy S. Salnikov;Evgeniy S. SalnikovUniversité de Strasbourg/CNRS, UMR7177Institut de Chimie, 1 rue Blaise Pascal67070StrasbourgFrance[email protected]Search for other works by this author on:Christopher Aisenbrey;Christopher AisenbreyUniversité de Strasbourg/CNRS, UMR7177Institut de Chimie, 1 rue Blaise Pascal67070StrasbourgFrance[email protected]Search for other works by this author on:Jesus Raya;Jesus RayaUniversité de Strasbourg/CNRS, UMR7177Institut de Chimie, 1 rue Blaise Pascal67070StrasbourgFrance[email protected]Search for other works by this author on:Burkhard BechingerBurkhard BechingerUniversité de Strasbourg/CNRS, UMR7177Institut de Chimie, 1 rue Blaise Pascal67070StrasbourgFrance[email protected]Search for other works by this author on:
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CHAPTER 13: NMR of Lipids and Lipid/Peptide Mixturesp235-266ByIvana KomljenovićIvana KomljenovićSearch for other works by this author on:
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CHAPTER 14: NMR Investigations of the Structure and Dynamics of Antimicrobial Peptides: The Peptaibol Alamethicinp267-286ByThomas Vosegaard;Thomas VosegaardCenter for Insoluble Protein Structures, Interdisciplinary Nanoscience Center and Department of Chemistry, Aarhus UniversityDenmarkSearch for other works by this author on:Niels Chr. NielsenNiels Chr. NielsenCenter for Insoluble Protein Structures, Interdisciplinary Nanoscience Center and Department of Chemistry, Aarhus UniversityDenmarkSearch for other works by this author on:
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CHAPTER 15: Solid-State NMR Studies of Antimicrobial Peptide Interactions with Specific Lipid Environmentsp287-303ByFrances SeparovicFrances SeparovicSearch for other works by this author on:
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CHAPTER 16: Dynamic Structure Analysis of Peptides in Membranes by Solid-State NMRp304-319ByErik Strandberg;Erik StrandbergKarlsruhe Institute for Technology (KIT), Institute for Biological Interfaces (IBG-2)P.O.B. 364076021KarlsruheGermanySearch for other works by this author on:Anne S. UlrichAnne S. UlrichKarlsruhe Institute for Technology (KIT), Institute for Biological Interfaces (IBG-2)P.O.B. 364076021KarlsruheGermanySearch for other works by this author on:
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CHAPTER 17: Structural Dynamics of Retinal in Rhodopsin Activation Viewed by Solid-State 2H NMR Spectroscopyp320-352ByMichael F. Brown;Michael F. BrownDepartment of Chemistry and Biochemistry, University of ArizonaTucson, AZ85721USADepartment of Physics, University of ArizonaTucson, AZ85721USASearch for other works by this author on:Andrey V. StrutsAndrey V. StrutsDepartment of Chemistry and Biochemistry, University of ArizonaTucson, AZ85721USALaboratory of Biomolecular NMR, St Petersburg State UniversitySt Petersburg199034Russia[email protected]Search for other works by this author on:
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CHAPTER 18: Helical Membrane Protein Structure: Strategy for Successp353-370ByNabanita Das;Nabanita DasNational High Magnetic Field Laboratory, Florida State UniversityTallahassee, FL32310USAInstitute of Molecular Biophysics, Florida State UniversityTallahassee, FL32306USASearch for other works by this author on:Dylan T. Murray;Dylan T. MurrayNational High Magnetic Field Laboratory, Florida State UniversityTallahassee, FL32310USAInstitute of Molecular Biophysics, Florida State UniversityTallahassee, FL32306USASearch for other works by this author on:Yimin Miao;Yimin MiaoNational High Magnetic Field Laboratory, Florida State UniversityTallahassee, FL32310USADepartment of Chemistry and Biochemistry, Florida State UniversityTallahassee, FL32306USA[email protected]Search for other works by this author on:Timothy A. CrossTimothy A. CrossNational High Magnetic Field Laboratory, Florida State UniversityTallahassee, FL32310USAInstitute of Molecular Biophysics, Florida State UniversityTallahassee, FL32306USADepartment of Chemistry and Biochemistry, Florida State UniversityTallahassee, FL32306USA[email protected]Search for other works by this author on:
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CHAPTER 19: Chemistry and Structure via Solid-State NMRp371-386ByJudith HerzfeldJudith HerzfeldSearch for other works by this author on:
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CHAPTER 20: Photoactivated Structural Changes in Photoreceptor Membrane Proteins as Revealed by in situ Photoirradiation Solid-State NMR Spectroscopyp387-404ByAkira Naito;Akira NaitoGraduate School of Engineering, Yokohama National University79-5 TokiwadaiHodogaya-ku, Yokohama240-8501Japan[email protected]Search for other works by this author on:Izuru KawamuraIzuru KawamuraGraduate School of Engineering, Yokohama National University79-5 TokiwadaiHodogaya-ku, Yokohama240-8501Japan[email protected]Search for other works by this author on:
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CHAPTER 21: A Promising Prognosis for Solid-State NMR of Functional Membrane Protein Complexesp405-424ByMichael J. Harris;Michael J. HarrisDepartmentof ChemistryandSearch for other works by this author on:Lynmarie K. ThompsonLynmarie K. ThompsonDepartmentof ChemistryandProgram in Molecular and Cellular Biology, University of MassachusettsAmherst, MA01003USA[email protected]Search for other works by this author on:
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CHAPTER 22: Structural Topologies of Phosphorylated and Non-phosphorylated Oligomeric Phospholamban in Lipid Membranes by a Hybrid NMR Approachp425-443ByVitaly Vostrikov;Vitaly VostrikovDepartment of BiochemistryMolecular Biology and BiophysicsSearch for other works by this author on:Gianluigi VegliaGianluigi VegliaDepartment of BiochemistryMolecular Biology and BiophysicsSearch for other works by this author on:
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CHAPTER 23: Structural Insights from Solid-State NMR into the Function of the Bacteriorhodopsin Photoreceptor Proteinp444-458ByAnthony WattsAnthony WattsSearch for other works by this author on:
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CHAPTER 24: 2H Solid-State NMR Study of Peptide–Membrane Interactions in Intact Bacteriap459-475ByIsabelle Marcotte;Isabelle MarcotteDepartment of ChemistryUniversité du Québec à Montréal, GRASP/CQMF, P.O. Box 8888, Downtown Station, MontréalCanadaH3C 3P8[email protected]Search for other works by this author on:Valerie BoothValerie BoothDepartment of Biochemistry and Department of Physics and Physical Oceanography, Memorial University of NewfoundlandSt. John's, NLCanadaA1B 3X9[email protected]Search for other works by this author on:
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CHAPTER 25: Magic Angle Spinning NMR Spectroscopy for Resolving Structure and Mechanisms of Function of Membrane Protein Assemblies Involved in Photosynthetic Energy Conversionp476-500ByHuub J. M. de GrootHuub J. M. de GrootSearch for other works by this author on:
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CHAPTER 26: Large Protein Complexes Revealed by Solution-State NMR: G Proteins and G Protein-Activated Inwardly Rectifying Potassium Ion Channelp501-532ByMasanori Osawa;Masanori OsawaGraduate School of Pharmaceutical Sciences, University of TokyoTokyoJapanSearch for other works by this author on:Yoko Mase;Yoko MaseGraduate School of Pharmaceutical Sciences, University of TokyoTokyoJapanSearch for other works by this author on:Mariko Yokogawa;Mariko YokogawaGraduate School of Pharmaceutical Sciences, University of TokyoTokyoJapanJapan Biological Information Research Centre (JBIRC), Japan Biological Informatics Consortium (JBIC)TokyoJapanSearch for other works by this author on:Koh Takeuchi;Koh TakeuchiMolecular Profiling Research Centre for Drug Discovery, National Institute of Advanced Industrial Science and Technology (AIST)TokyoJapan[email protected]Search for other works by this author on:Ichio ShimadaIchio ShimadaGraduate School of Pharmaceutical Sciences, University of TokyoTokyoJapanSearch for other works by this author on:
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CHAPTER 27: NMR Studies of Small Molecules Interacting with Amyloidogenic Proteinsp533-555ByElke Prade;Elke PradeHelmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und UmweltIngolstädter Landstr. 185764NeuherbergGermanyMunich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM)Lichtenbergstr. 485747GarchingGermanySearch for other works by this author on:Juan-Miguel Lopez del Amo;Juan-Miguel Lopez del AmoHelmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und UmweltIngolstädter Landstr. 185764NeuherbergGermanyMunich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM)Lichtenbergstr. 485747GarchingGermanySearch for other works by this author on:Bernd ReifBernd ReifHelmholtz-Zentrum München (HMGU), Deutsches Forschungszentrum für Gesundheit und UmweltIngolstädter Landstr. 185764NeuherbergGermanyMunich Center for Integrated Protein Science (CIPS-M) at Department Chemie, Technische Universität München (TUM)Lichtenbergstr. 485747GarchingGermanySearch for other works by this author on:
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CHAPTER 28: Solid-State NMR Studies of β-Amyloid Fibrils and Related Assembliesp556-576ByWei Qiang;Wei QiangLaboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of HealthBethesda, MD20892-0520USA[email protected]Search for other works by this author on:Robert TyckoRobert TyckoLaboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of HealthBethesda, MD20892-0520USA[email protected]Search for other works by this author on:
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