Cell Surface Engineering: Fabrication of Functional Nanoshells
CHAPTER 2: Functional Multilayered Polyelectrolyte Assemblies on Biological Cells
Published:08 Jul 2014
Ben Wang, 2014. "Functional Multilayered Polyelectrolyte Assemblies on Biological Cells", Cell Surface Engineering: Fabrication of Functional Nanoshells, Rawil Fakhrullin, Insung Choi, Yuri Lvov
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Layer-by-layer assembly has been explored as a general approach for interface modification and engineering. In the recent past, increasing interest has been attracted for functional multilayered polyelectrolyte assemblies on biological cells. Here we summarize layer-by-layer polyelectrolyte/particles assembly on different kinds of cells, from microbes, such as fungi, bacteria and viruses, to mammal cells, and even for multicellular organisms. The toxicity of polyelectrolytes used in this process is evaluated and the mechanisms are also given in detail. Finally, conclusions and perspectives are given.