Skip to Main Content
Skip Nav Destination

Raloxifene, as shown in Figure 5.1, is a classic example of a selective estrogen receptor modulator (SERM)1–7  and a number of studies indicate that the binding affinity of raloxifene is about one third of the binding affinity of estradiol8,9  to the estrogen receptor. It is an estrogen agonist/antagonist, commonly referred to as a SERM that has benzothiopheneheterocyclic moiety.

It an extensively investigated SERM that partially simulates the effect of estrogens in bone and the cardiovascular system, while functioning as an anti-estrogen in endometrial and breast tissues. It has been approved for the prevention of osteoporosis and reduction...

You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Don't already have an account? Register
Close Modal

or Create an Account

Close Modal
Close Modal