Thermometry at the Nanoscale: Techniques and Selected Applications
Chapter 5: Luminescent Nanothermometry with Lanthanide-doped Nanoparticles
Published:02 Oct 2015
Marta Quintanilla, Antonio Benayas, Rafik Naccache, Fiorenzo Vetrone, 2015. "Luminescent Nanothermometry with Lanthanide-doped Nanoparticles", Thermometry at the Nanoscale: Techniques and Selected Applications, Luís Dias Carlos, Fernando Palacio
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In recent years, nanomaterials have come to light with the potential of revolutionizing current approaches to the development of novel materials and tools. It is in this regard that there has been a large body of work dedicated to the study and integration of these materials at the nanoscale with the goal of improving existing devices or further, to develop altogether new nanoscale devices and technologies.1–7 A specific focus has been on optical nanoparticles such as semiconductor quantum dots (QDs) and noble metal nanomaterials (silver nanoparticles, gold nanoparticles/nanorods) for their implementation in biological applications and nanomedicine.8–15 This small (or nano) revolution is bringing forth the possibility of personalized nanomedicine with the simultaneous ability to target specific biological sites, detect disease by providing diagnostic information by one or more techniques (fluorescent imaging, magnetic resonance imaging, thermal sensing, etc.) and deliver a localized therapeutic modality (photodynamic therapy, photothermal therapy, drug release, or combinations thereof). This theranostic approach to medicine has the potential to bring forth a paradigm shift in the biomedical landscape. Not only will such an approach result in the reduction of the vast and mounting costs associated with healthcare, but will also ensure a more rapid intervention for patients and will eventually translate to a greater probability of therapeutic success.