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Issues in Toxicology
The Comet Assay in Toxicology
Edited by
Alok Dhawan
Alok Dhawan
Centre of Biomedical Research, Lucknow, India
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Hardback ISBN:
978-1-78262-287-1
PDF ISBN:
978-1-78262-289-5
EPUB ISBN:
978-1-78262-915-3
Special Collection:
2016 ebook collection
Series:
Issues in Toxicology
Published online:
11 Oct 2016
Published in print:
07 Oct 2016
Book Chapter
Chapter 6: Development and Applications of the Comet-FISH Assay for the Study of DNA Damage and Repair
By
Valerie J. Mckelvey-Martin
;
Valerie J. Mckelvey-Martin
Biomedical Sciences Research Institute, University of Ulster
Coleraine
BT52 ISA
Northern Ireland
UK
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Declan J. Mckenna
Declan J. Mckenna
Biomedical Sciences Research Institute, University of Ulster
Coleraine
BT52 ISA
Northern Ireland
UK
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Published:07 Oct 2016
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Special Collection: 2016 ebook collectionSeries: Issues in Toxicology
Page range:
143 - 163
Citation
V. J. Mckelvey-Martin and D. J. Mckenna, in The Comet Assay in Toxicology, ed. D. Anderson and A. Dhawan, The Royal Society of Chemistry, 2nd edn, 2016, ch. 6, pp. 143-163.
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This review discusses the methods for employing the Comet-FISH assay in the laboratory and summarises the various studies that have successfully used this approach, examining the different applications and uses of this versatile technique. The potential and limitations of the assay are also considered and the importance of these limitations on accurate data interpretation is emphasised.
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