Skip Nav Destination
Issues in Toxicology
The Comet Assay in Toxicology
Edited by
Alok Dhawan
Alok Dhawan
Centre of Biomedical Research, Lucknow, India
Search for other works by this author on:
Hardback ISBN:
978-1-78262-287-1
PDF ISBN:
978-1-78262-289-5
EPUB ISBN:
978-1-78262-915-3
Special Collection:
2016 ebook collection
Series:
Issues in Toxicology
Publication date:
07 Oct 2016
Book Chapter
Chapter 19: Imaging and Image Analysis in the Comet Assay
By
Mark Browne
Mark Browne
Search for other works by this author on:
-
Published:07 Oct 2016
-
Special Collection: 2016 ebook collectionSeries: Issues in Toxicology
Page range:
515 - 550
Citation
M. Browne, in The Comet Assay in Toxicology, ed. D. Anderson and A. Dhawan, The Royal Society of Chemistry, 2nd edn, 2016, ch. 19, pp. 515-550.
Download citation file:
Imaging and image analysis provides the vital link between the “wet” comet assay and statistical analysis of results. Therefore, in this chapter we consider all aspects of the process including: fluorescent labelling of DNA; function, selection and care of microscope components; evolution of light sources; camera technologies; digital image processing leading to quantitative analysis of comet DNA distributions; database storage and management of results; and finally, data preparation for statistical analysis in the light of the recent OECD test guideline TG489.
You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Digital access
$64.60
