Skip Nav Destination
Metallobiology
2-Oxoglutarate-Dependent Oxygenases
Edited by
Christopher Schofield;
Christopher Schofield
University of Oxford, UK
Search for other works by this author on:
Robert Hausinger
Robert Hausinger
Michigan State University, USA
Search for other works by this author on:
Hardback ISBN:
978-1-84973-950-4
PDF ISBN:
978-1-78262-195-9
EPUB ISBN:
978-1-78262-500-1
No. of Pages:
487
Publication date:
23 Apr 2015
Book Chapter
CHAPTER 7: JmjC Lysine Demethylases
By
Xiaodong Cheng
;
Xiaodong Cheng
Department of Biochemistry, Emory University
Atlanta
GA 30322
USA
Search for other works by this author on:
Raymond C. Trievel
Raymond C. Trievel
Search for other works by this author on:
-
Published:23 Apr 2015
-
Citation
X. Cheng and R. C. Trievel, in 2-Oxoglutarate-Dependent Oxygenases, ed. C. Schofield and R. Hausinger, The Royal Society of Chemistry, 2015, pp. 210-245.
Download citation file:
Among the most fundamental questions in the regulation of gene expression in mammals is how epigenetic methylation patterns of histone lysine residues are established, recognized and erased. This chapter reviews recent studies on, and discusses the resulting biochemical and structural insights into, the Jumonji C (JmjC)-containing lysine demethylases (KDMs), focusing on their biological functions, three-dimensional structures, mechanism and substrate specificities.
You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Digital access
$64.60
