Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry
Chapter 14: Synthetic Biology for Organic Syntheses
Published:08 Mar 2016
B. Wiltschi and A. Glieder, in Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry, ed. L. Summerton, H. F. Sneddon, L. C. Jones, and J. H. Clark, The Royal Society of Chemistry, 2016, ch. 14, pp. 165-179.
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In this chapter, we explore the chances as well as the limitations of synthetic biology for green chemistry. We briefly introduce the principles of synthetic biology for the design and synthesis of new biological systems. For two hallmark examples, the biosynthesis of artemisinic acid and vanillin in microbial hosts, we illustrate how green chemistry can benefit from the support of synthetic biology.