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Green Chemistry Series
Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry
Edited by
James H Clark
James H Clark
University of York, UK
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Hardback ISBN:
978-1-78262-467-7
PDF ISBN:
978-1-78262-594-0
EPUB ISBN:
978-1-78262-747-0
Series:
Green Chemistry
No. of Pages:
272
Publication date:
08 Mar 2016
Book Chapter
Chapter 9: Medicinal Chemistry: How “Green” is Our Synthetic Tool Box?
By
Sirpa Rasku
Sirpa Rasku
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Published:08 Mar 2016
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Series: Green Chemistry
Citation
J. Messinger, L. Otsomaa, and S. Rasku, in Green and Sustainable Medicinal Chemistry: Methods, Tools and Strategies for the 21st Century Pharmaceutical Industry, ed. L. Summerton, H. F. Sneddon, L. C. Jones, and J. H. Clark, The Royal Society of Chemistry, 2016, ch. 9, pp. 101-115.
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Medicinal chemistry departments in pharmaceutical companies or research institutes are considered to be providers of new chemical entities for testing in biological systems on mg and g scales. Time, yields and flexibility of a reaction play a major role during the optimisation cycles. Current standards of synthetic tools and techniques are discussed under the viewpoint of environmental aspects.
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