Theranostics and Image Guided Drug Delivery
Molecular imaging of drugs or drug carriers is a valuable tool that can provide important information on spatiotemporal distribution of drugs, allowing improved drug distribution at target sites. Chemically labelled drugs can be used to both diagnose and treat diseases. This book introduces the topic of image guided drug delivery and covers the latest imaging techniques and developments in theranostics, highlighting the interdisciplinary nature of this field as well as its translational ability. These technologies and techniques hold potential for individualised, safer therapies.
The book introduces the chemistry behind labelling drugs or drug carriers for imaging. It then discusses current scientific progress in the discovery and development of theranostic agents as well as the latest advances in triggered drug delivery. Novel imaging techniques that can be combined with therapeutics are presented, as well as results and findings from early clinical trials.
This text will provide postgraduates and researchers in various disciplines associated with drug discovery, including chemistry, device engineering, oncology, neurology, cardiology, imaging, and nanoscience, an overview of this important field where several disciplines have been combined to improve treatments. Readers will be introduced to techniques that can be translated to the clinic and be applied widely.
Theranostics and Image Guided Drug Delivery, The Royal Society of Chemistry, 2018.
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Table of contents
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CHAPTER 1: Image Guided Focused Ultrasound as a New Method of Targeted Drug Deliveryp1-28ByM. Wright;M. WrightInstitute of Pharmaceutical Science, King’s College LondonLondonUKSearch for other works by this author on:M. Centelles;M. CentellesInstitute of Pharmaceutical Science, King’s College LondonLondonUKSearch for other works by this author on:M. ThanouM. ThanouInstitute of Pharmaceutical Science, King’s College LondonLondonUKSearch for other works by this author on:
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CHAPTER 2: Image-guided Drug Delivery Systems Based on NIR-absorbing Nanocarriers for Photothermal-chemotherapy of Cancerp29-52ByJinping Wang;Jinping WangSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:Xiaoxiao Tan;Xiaoxiao TanSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:Xiaojuan Pang;Xiaojuan PangSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:Qing You;Qing YouSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:Li Liu;Li LiuSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:Qi Sun;Qi SunSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:Fengping Tan;Fengping TanSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:Nan LiNan LiSchool of Pharmaceutical Science and Technology, Tianjin University300072TianjinPR China[email protected]Search for other works by this author on:
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CHAPTER 3: Applications of Magnetic Nanoparticles in Multi-modal Imagingp53-85ByJ. T.-W. Wang;J. T.-W. WangInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College LondonFranklin-Wilkins BuildingLondon SE19 NHUnited Kingdom[email protected]Search for other works by this author on:J. Bai;J. BaiInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College LondonFranklin-Wilkins BuildingLondon SE19 NHUnited Kingdom[email protected]Search for other works by this author on:K. T. Al-JamalK. T. Al-JamalInstitute of Pharmaceutical Science, Faculty of Life Sciences & Medicine, King's College LondonFranklin-Wilkins BuildingLondon SE19 NHUnited Kingdom[email protected]Search for other works by this author on:
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CHAPTER 4: Photodynamic Therapyp86-122ByCormac Hally;Cormac HallyInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]Search for other works by this author on:Beatriz Rodríguez-Amigo;Beatriz Rodríguez-AmigoInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]Search for other works by this author on:Roger Bresolí-Obach;Roger Bresolí-ObachInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]Search for other works by this author on:Oriol Planas;Oriol PlanasInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]Search for other works by this author on:Jaume Nos;Jaume NosInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]Search for other works by this author on:Ester Boix-Garriga;Ester Boix-GarrigaInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]School of Pharmaceutical Sciences, University of Geneva, University of LausanneGenevaSwitzerlandSearch for other works by this author on:Rubén Ruiz-González;Rubén Ruiz-GonzálezInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]Search for other works by this author on:Santi NonellSanti NonellInstitut Químic de Sarrià, Universitat Ramon LlullVia Augusta 39008017 BarcelonaSpain[email protected]Search for other works by this author on:
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CHAPTER 5: Radiolabelling Liposomal Nanomedicines for PET Imagingp123-136ByRafael T. M. de RosalesRafael T. M. de RosalesDivision of Imaging Sciences & Biomedical Engineering, King's College London, St. Thomas' HospitalSE1 7EHLondonUK[email protected]Search for other works by this author on:
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CHAPTER 6: Liposomes for Hyperthermia Triggered Drug Releasep137-163ByW. J. M. Lokerse;W. J. M. LokerseDepartment of Internal Medicine III, University Hospital of Munich, Ludwig-Maximilians University MunichMarchioninistrasse 15MunichD-81377Germany[email protected]Search for other works by this author on:B. Kneidl;B. KneidlDepartment of Internal Medicine III, University Hospital of Munich, Ludwig-Maximilians University MunichMarchioninistrasse 15MunichD-81377Germany[email protected]Search for other works by this author on:A. Rysin;A. RysinDepartment of Internal Medicine III, University Hospital of Munich, Ludwig-Maximilians University MunichMarchioninistrasse 15MunichD-81377Germany[email protected]Search for other works by this author on:M. Petrini;M. PetriniDepartment of Internal Medicine III, University Hospital of Munich, Ludwig-Maximilians University MunichMarchioninistrasse 15MunichD-81377Germany[email protected]Search for other works by this author on:L. H. LindnerL. H. LindnerDepartment of Internal Medicine III, University Hospital of Munich, Ludwig-Maximilians University MunichMarchioninistrasse 15MunichD-81377Germany[email protected]Search for other works by this author on:
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CHAPTER 7: Targeted Delivery with Ultrasound Activated Nano-encapsulated Drugsp164-181ByS. CochranS. CochranGlasgow UniversityUKSearch for other works by this author on:
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CHAPTER 8: Theranostics in the Gutp182-210ByFraser Stewart;Fraser StewartSchool of Life Sciences, University of DundeeDundeeDD1 4HNUKSearch for other works by this author on:Inke Näthke;Inke NäthkeSchool of Life Sciences, University of DundeeDundeeDD1 4HNUKSearch for other works by this author on:Sandy CochranSandy CochranSearch for other works by this author on:
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CHAPTER 9: Microwave Imaging and the Potential of Contrast Enhancing Agents for Theranostics Usep211-233ByR. Lahri;R. LahriKing’s College London, Institute of Pharmaceutical Science150 Stamford StreetLondonSE19NHUK[email protected]Search for other works by this author on:M. Rahman;M. RahmanKing’s College London, Institute of Pharmaceutical Science150 Stamford StreetLondonSE19NHUK[email protected]Search for other works by this author on:P. Kosmas;P. KosmasKing’s College London, Department of InformaticsStrandLondonWC2R 2LSUKSearch for other works by this author on:M. ThanouM. ThanouKing’s College London, Institute of Pharmaceutical Science150 Stamford StreetLondonSE19NHUK[email protected]Search for other works by this author on:
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