Mass Spectrometry in Chemical Biology: Evolving Applications
Mass spectrometry is one of the most widespread technologies in chemistry and has been increasingly used in biology with the rise of omics sciences. This book summarizes some important methodological approaches in mass spectrometry and applications in the field of chemical biology.
The core chapters build on basic concepts introduced in the opening chapter and explore established fields such as high throughput screening, proteomics and metabolomics. Emerging applications of mass spectrometry in elucidating biosynthetic pathways, enzyme mechanisms and protein-protein interactions are then presented. Connections between these diverse research fields are highlighted throughout. The book concludes with a discussion of databases and future perspectives.
This book will be a useful tool to early chemical biology researchers wishing to incorporate mass spectrometry as a tool in their research.
Mass Spectrometry in Chemical Biology: Evolving Applications, The Royal Society of Chemistry, 2017.
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CHAPTER 2: Introduction to Mass Spectrometry Instrumentation and Methods Used in Chemical Biologyp17-56ByP. Herrero;P. HerreroUniversitat Rovira i Virgili, Centre for Omic Sciences (COS), Group of Research on Omics Methodologies (GROM)Av. Universitat 1Reus43204Spain[email protected]Search for other works by this author on:A. Delpino-Rius;A. Delpino-RiusUniversitat Rovira i Virgili, Centre for Omic Sciences (COS), Group of Research on Omics Methodologies (GROM)Av. Universitat 1Reus43204Spain[email protected]Search for other works by this author on:M. R. Ras-Mallorquí;M. R. Ras-MallorquíUniversitat Rovira i Virgili, Centre for Omic Sciences (COS), Group of Research on Omics Methodologies (GROM)Av. Universitat 1Reus43204Spain[email protected]Search for other works by this author on:L. Arola;L. ArolaCentre Tecnològic de Nutrició i Salut (CTNS)Av. Universitat 1Reus43204SpainSearch for other works by this author on:N. CanelaN. CanelaUniversitat Rovira i Virgili, Centre for Omic Sciences (COS), Group of Research on Omics Methodologies (GROM)Av. Universitat 1Reus43204Spain[email protected]Search for other works by this author on:
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CHAPTER 3: Metabolomicsp57-81ByRicardo R. da Silva;Ricardo R. da SilvaNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSPBrazil[email protected]Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of CaliforniaSan Diego, La JollaCA 92093USASearch for other works by this author on:Norberto Peporine Lopes;Norberto Peporine LopesNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSPBrazil[email protected]Search for other works by this author on:Denise Brentan SilvaDenise Brentan SilvaNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSPBrazil[email protected]Laboratório de Produtos Naturais e Espectrometria de Massas (LAPNEM), Faculdade de Ciências Farmacêuticas, Alimentos e Nutrição (FACFAN), Universidade Federal de Mato Grosso do Sul (UFMS)Campo GrandeMSBrazilSearch for other works by this author on:
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CHAPTER 4: Proteomicsp82-143BySwati Varshney;Swati VarshneyGenomics and Molecular Medicine unit, CSIR-Institute of Genomics and Integrative BiologySukhdev Vihar, Mathura RoadNew Delhi 110 020IndiaAcademy of Scientific & Innovative Research (AcSIR), CSIR-IGIB South CampusNew Delhi 110 020India[email protected]Search for other works by this author on:Trayambak Basak;Trayambak BasakDepartment of Medicine, Division of Nephrology and Hypertension, Vanderbilt University Medical CenterNashvilleTennessee 37232United StatesSearch for other works by this author on:Mainak Dutta;Mainak DuttaGenomics and Molecular Medicine unit, CSIR-Institute of Genomics and Integrative BiologySukhdev Vihar, Mathura RoadNew Delhi 110 020IndiaBirla Institute of Technology Pilani, Dubai CampusDubai International Academic City, P. O. Box No. 345055DubaiUnited Arab EmiratesSearch for other works by this author on:Shantanu SenguptaShantanu SenguptaGenomics and Molecular Medicine unit, CSIR-Institute of Genomics and Integrative BiologySukhdev Vihar, Mathura RoadNew Delhi 110 020IndiaAcademy of Scientific & Innovative Research (AcSIR), CSIR-IGIB South CampusNew Delhi 110 020India[email protected]Search for other works by this author on:
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CHAPTER 5: Mass Spectrometry for Discovering Natural Productsp144-158ByPaulo C. Vieira;Paulo C. VieiraDepartment of Chemistry, Federal University of São CarlosSao CarlosSP13565-905Brazil[email protected]Search for other works by this author on:Ana Carolina A. Santos;Ana Carolina A. SantosDepartment of Chemistry, Federal University of São CarlosSao CarlosSP13565-905Brazil[email protected]Search for other works by this author on:Taynara L. SilvaTaynara L. SilvaDepartment of Chemistry, Federal University of São CarlosSao CarlosSP13565-905Brazil[email protected]Search for other works by this author on:
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CHAPTER 6: Applications of Mass Spectrometry in Synthetic Biologyp159-172ByZaira Bruna Hoffmam;Zaira Bruna HoffmamBrazilian Bioethanol Science and Technology Laboratory (CTBE)Rua Giuseppe Máximo Scolfaro 10.000 CEP 13083-100 CampinasSão PauloBrazilSearch for other works by this author on:Viviane Cristina Heinzen da Silva;Viviane Cristina Heinzen da SilvaBrazilian Bioethanol Science and Technology Laboratory (CTBE)Rua Giuseppe Máximo Scolfaro 10.000 CEP 13083-100 CampinasSão PauloBrazilSearch for other works by this author on:Marina C. M. Martins;Marina C. M. MartinsBrazilian Bioethanol Science and Technology Laboratory (CTBE)Rua Giuseppe Máximo Scolfaro 10.000 CEP 13083-100 CampinasSão PauloBrazilSearch for other works by this author on:Camila CaldanaCamila CaldanaBrazilian Bioethanol Science and Technology Laboratory (CTBE)Rua Giuseppe Máximo Scolfaro 10.000 CEP 13083-100 CampinasSão PauloBrazilMax Planck Partner Group at Brazilian Bioethanol Science and Technology LaboratoryBrazil[email protected]Search for other works by this author on:
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CHAPTER 7: Studying Enzyme Mechanisms Using Mass Spectrometry, Part 1: Introductionp173-196ByDerek J. WilsonDerek J. WilsonCentre for Research of Biomolecular Interactions, York UniversityTorontoM3J 1P3CanadaCentre for Research in Mass Spectrometry, York UniversityTorontoM3J 1P3CanadaSearch for other works by this author on:
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CHAPTER 8: Studying Enzyme Mechanisms Using Mass Spectrometry, Part 2: Applicationsp197-220ByPeter Liuni;Peter LiuniDepartment of Chemistry, York UniversityTorontoM3J 1P3CanadaSearch for other works by this author on:Cristina Lento;Cristina LentoCentre for Research of Biomolecular Interactions, York UniversityTorontoM3J 1P3CanadaSearch for other works by this author on:Derek J. WilsonDerek J. WilsonDepartment of Chemistry, York UniversityTorontoM3J 1P3CanadaCentre for Research of Biomolecular Interactions, York UniversityTorontoM3J 1P3CanadaSearch for other works by this author on:
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CHAPTER 9: Chemical Biology Databasesp221-263ByAlan C. Pilon;Alan C. PilonNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSão PauloBrazil[email protected]Search for other works by this author on:Ana Paez-Garcia;Ana Paez-GarciaNoble Research Institute LLCArdmoreOklahomaUSASearch for other works by this author on:Daniel Petinatti Pavarini;Daniel Petinatti PavariniNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSão PauloBrazil[email protected]Search for other works by this author on:Marcus Tullius ScottiMarcus Tullius ScottiDepartamento de Química, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba - Campus IJoão PessoaBrazilSearch for other works by this author on:
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CHAPTER 10: Perspectives for the Futurep264-287ByAnelize Bauermeister;Anelize BauermeisterNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSão PauloBrazil[email protected]Search for other works by this author on:Larissa A. Rolim;Larissa A. RolimNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSão PauloBrazil[email protected]Central de Análise de Fármacos, Medicamentos e Alimentos (CAFMA), Universidade Federal do Vale do São FranciscoPetrolinaPernambucoBrazilSearch for other works by this author on:Ricardo Silva;Ricardo SilvaCollaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of CaliforniaSan DiegoLa JollaCA 92093USASearch for other works by this author on:Paul J. Gates;Paul J. GatesSchool of Chemistry, University of BristolCliftonBristolBS8 1TSUKSearch for other works by this author on:Norberto Peporine LopesNorberto Peporine LopesNúcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São PauloRibeirão PretoSão PauloBrazil[email protected]Search for other works by this author on:
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