Supramolecular Chemistry in Biomedical Imaging
There have been many great advances in the field of biomedical imaging in recent years, with supramolecular chemistry playing a key role in the evolution of modern imaging techniques. Non-covalent supramolecular interactions are fundamental to countless biological processes, from host–guest binding to the stabilisation of complex structures. Supramolecular chemistry techniques can be employed to create probes that can be targeted to either exploit or disrupt these interactions, giving the potential for both diagnostic and therapeutic effects. Furthermore, in techniques such as contrast enhanced MRI, controlling the interactions between solvent molecules and the imaging agent is crucial to the development of the technique.
With rapid growth in the synthesis and study of molecular imaging agents, the understanding of their associated techniques has sometimes lagged behind. Supramolecular Chemistry in Biomedical Imaging will fill this gap by clarifying the state of current understanding and the nature of the underlying problems inherent to addressing problems in biology. It will cover both the techniques used in imaging and the molecular and supramolecular systems used to exploit them.
This publication targets academics coming to the field from mainstream supramolecular chemistry, research graduates and undergraduates interested in supramolecular chemistry, synthesis or imaging agents and imaging techniques for biomedical applications.
Supramolecular Chemistry in Biomedical Imaging, The Royal Society of Chemistry, 2022.
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CHAPTER 1: Targeting Supramolecular Imaging Agents for a Wide Range of Applicationsp1-42ByElena Calatrava-Pérez;Elena Calatrava-PérezSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2Ireland[email protected]Search for other works by this author on:Esther Surender;Esther SurenderSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2Ireland[email protected]Search for other works by this author on:Laura Truman;Laura TrumanSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2Ireland[email protected]Search for other works by this author on:GearÓid M. Ó Máille;GearÓid M. Ó MáilleSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2Ireland[email protected]Search for other works by this author on:Adam Francis Henwood;Adam Francis HenwoodSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2Ireland[email protected]Search for other works by this author on:Eoin Scanlan;Eoin ScanlanSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2Ireland[email protected]Search for other works by this author on:Thorfinnur GunnlaugssonThorfinnur GunnlaugssonSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2Ireland[email protected]Search for other works by this author on:
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CHAPTER 2: Optical Spectroscopies: Detection of Biological Species, Conformations and Interactionsp43-67ByNathan D. McClenaghan;Nathan D. McClenaghanInstitut des Sciences Moléculaires, CNRS UMR 5255, Université de Bordeaux351 Cours de la LibérationTalence33405France[email protected][email protected]Search for other works by this author on:Vincent RodriguezVincent RodriguezInstitut des Sciences Moléculaires, CNRS UMR 5255, Université de Bordeaux351 Cours de la LibérationTalence33405France[email protected][email protected]Search for other works by this author on:
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CHAPTER 3: Super-resolution Microscopyp68-88ByEdward N. Ward;Edward N. WardUniversity of Cambridge, Department of Chemical Engineering and BiotechnologyPhilippa Fawcett DriveCambridgeCB1 0ASUKSearch for other works by this author on:Robert PalRobert PalSearch for other works by this author on:
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CHAPTER 4: The Role of Fundamental Coordination Chemistry in the Development of Radioimaging Agentsp89-148ByMark Bartholomae;Mark BartholomaeDepartment of Nuclear Medicine, Saarland University – Medical Center66421 HomburgGermanySearch for other works by this author on:Nerissa Viola-Villegas;Nerissa Viola-VillegasDepartment of Oncology, Karmanos Cancer Institute, Wayne State UniversityDetroitMI 48202USASearch for other works by this author on:Jayme L. Workinger;Jayme L. WorkingerDepartment of Chemistry, 111 College Place, Syracuse UniversitySyracuseNY 13244USA[email protected][email protected]Search for other works by this author on:Robert P. Doyle;Robert P. DoyleDepartment of Chemistry, 111 College Place, Syracuse UniversitySyracuseNY 13244USA[email protected][email protected]Search for other works by this author on:Jon ZubietaJon ZubietaDepartment of Chemistry, 111 College Place, Syracuse UniversitySyracuseNY 13244USA[email protected][email protected]Search for other works by this author on:
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CHAPTER 5: Supramolecular Aspects of Magnetic Resonance Imagingp149-162ByGearóid M. Ó MáilleGearóid M. Ó MáilleTrinity College Dublin, Department of ChemistryDublin 2IrelandSearch for other works by this author on:
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CHAPTER 6: Lanthanide Containing Systems for Molecular Magnetic Resonance Imaging and Therapyp163-206BySara Lacerda;Sara LacerdaCentre de Biophysique Moléculaire, CNRS UPR 4301, Université d'OrléansRue Charles SadronOrléans45071France[email protected]Search for other works by this author on:Kristina Djanashvili;Kristina DjanashviliDelft University of Technology, Department of BiotechnologyVan der Maasweg 92629HZDelftThe NetherlandsSearch for other works by this author on:Célia S. BonnetCélia S. BonnetCentre de Biophysique Moléculaire, CNRS UPR 4301, Université d'OrléansRue Charles SadronOrléans45071France[email protected]Search for other works by this author on:
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CHAPTER 7: Molecular Imaging in Diagnosis and Treatment of Brain Tumoursp207-241ByNicola J. Farrer;Nicola J. FarrerUniversity of Oxford, Chemistry Research Laboratory12 Mansfield RoadOxfordOX1 3TAUK[email protected]Search for other works by this author on:Rhiannon J. Evans;Rhiannon J. EvansImperial College London, Department of ChemistryWhite CityLondonW12 0BZUKSearch for other works by this author on:Sophie V. Morse;Sophie V. MorseImperial College London, Department of BioengineeringSouth KensingtonLondonSW7 2AZUKSearch for other works by this author on:Nicholas J. LongNicholas J. LongImperial College London, Department of ChemistryWhite CityLondonW12 0BZUKSearch for other works by this author on:
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CHAPTER 8: Carbon Nanomaterials for Imagingp242-277ByStefania Lettieri;Stefania LettieriIstituto Italiano di Tecnologia (IIT), Nano Carbon MaterialsVia Livorno 6010144TurinItalySearch for other works by this author on:Marta d'Amora;Marta d'AmoraIstituto Italiano di Tecnologia (IIT), Nano Carbon MaterialsVia Livorno 6010144TurinItalySearch for other works by this author on:Silvia GiordaniSilvia GiordaniSearch for other works by this author on:
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CHAPTER 9: Quantum Dots in Biological Imagingp278-321ByIrina V. Martynenko;Irina V. MartynenkoITMO University49 Kronverksky Pr.St. Petersburg197101 RussiaSearch for other works by this author on:Finn Purcell-Milton;Finn Purcell-MiltonBEACON, Bioeconomy SFI Research Centre, University College DublinDublin 4IrelandSearch for other works by this author on:Yurii K. Gun'koYurii K. Gun'koBEACON, Bioeconomy SFI Research Centre, University College DublinDublin 4IrelandSearch for other works by this author on:
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CHAPTER 10: Future Directions in Biomedical Imaging Using Supramolecular Chemistryp322-326ByThorfinnur Gunnlaugsson;Thorfinnur GunnlaugssonSchool of Chemistry, Trinity College Dublin, The University of DublinDublin 2IrelandSearch for other works by this author on:Nathan D. McClenaghan;Nathan D. McClenaghanInstitut des Sciences Moléculaires, CNRS UMR 5255, Université de Bordeaux351 cours de la LibérationTalence33405FranceSearch for other works by this author on:Robert Pal;Robert PalDurham University, Department of ChemistrySouth RoadDurhamDH1 1PXUKSearch for other works by this author on:Robert P. Doyle;Robert P. DoyleDepartment of Chemistry, 111 College Place, Syracuse UniversitySyracuseNY 13244USASearch for other works by this author on:Jon Zubieta;Jon ZubietaDepartment of Chemistry, 111 College Place, Syracuse UniversitySyracuseNY 13244USASearch for other works by this author on:Célia S. Bonnet;Célia S. BonnetCentre de Biophysique Moléculaire, CNRS UPR 4301, Université d'Orléans, Rue Charles SadronOrléans45071FranceSearch for other works by this author on:Silvia Giordani;Silvia GiordaniSchool of Chemical Sciences, Dublin City UniversityGlasnevinDublin 9IrelandSearch for other works by this author on:Irina V. Martynenko;Irina V. MartynenkoITMO University49 Kronverksky Pr.St. Petersburg197101 RussiaSearch for other works by this author on:Finn Purcell-Milton;Finn Purcell-MiltonSchool of Chemistry and CRANN, Trinity College DublinDublin 2IrelandBEACON, Bioeconomy SFI Research Centre, University College DublinDublin 4IrelandSearch for other works by this author on:Yurii K. Gun'koYurii K. Gun'koSchool of Chemistry and CRANN, Trinity College DublinDublin 2IrelandBEACON, Bioeconomy SFI Research Centre, University College DublinDublin 4IrelandSearch for other works by this author on:
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