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Antibiotic Drug Discovery

New Targets and Molecular Entities

Drug Discovery Series

Editor-in-chief

David Thurston, King’s College, UK

Series editors:

David Fox, Vulpine Science and Learning, UK

Ana Martinez, Centro de Investigaciones Biologicas-CSIC, Spain

David Rotella, Montclair State University, USA

Sarah Skerratt, Convergence, UK

Editorial advisor:

Hong Shen, Roche Innovation Center Shanghai, China

Titles in the Series:

1: Metabolism, Pharmacokinetics and Toxicity of Functional Groups

2: Emerging Drugs and Targets for Alzheimer’s Disease; Volume 1

3: Emerging Drugs and Targets for Alzheimer’s Disease; Volume 2

4: Accounts in Drug Discovery

5: New Frontiers in Chemical Biology

6: Animal Models for Neurodegenerative Disease

7: Neurodegeneration

8: G Protein-Coupled Receptors

9: Pharmaceutical Process Development

10: Extracellular and Intracellular Signaling

11: New Synthetic Technologies in Medicinal Chemistry

12: New Horizons in Predictive Toxicology

13: Drug Design Strategies: Quantitative Approaches

14: Neglected Diseases and Drug Discovery

15: Biomedical Imaging

16: Pharmaceutical Salts and Cocrystals

17: Polyamine Drug Discovery

18: Proteinases as Drug Targets

19: Kinase Drug Discovery

20: Drug Design Strategies: Computational Techniques and Applications

21: Designing Multi-Target Drugs

22: Nanostructured Biomaterials for Overcoming Biological Barriers

23: Physico-Chemical and Computational Approaches to Drug Discovery

24: Biomarkers for Traumatic Brain Injury

25: Drug Discovery from Natural Products

26: Anti-Inflammatory Drug Discovery

27: New Therapeutic Strategies for Type 2 Diabetes: Small Molecules

28: Drug Discovery for Psychiatric Disorders

29: Organic Chemistry of Drug Degradation

30: Computational Approaches to Nuclear Receptors

31: Traditional Chinese Medicine

32: Successful Strategies for the Discovery of Antiviral Drugs

33: Comprehensive Biomarker Discovery and Validation for Clinical Application

34: Emerging Drugs and Targets for Parkinson's Disease

35: Pain Therapeutics; Current and Future Treatment Paradigms

36: Biotherapeutics: Recent Developments using Chemical and Molecular Biology

37: Inhibitors of Molecular Chaperones as Therapeutic Agents

38: Orphan Drugs and Rare Diseases

39: Ion Channel Drug Discovery

40: Macrocycles in Drug Discovery

41: Human-based Systems for Translational Research

42: Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics

43: Carbohydrates in Drug Design and Discovery

44: Drug Discovery for Schizophrenia

45: Cardiovascular and Metabolic Disease: Scientific Discoveries and New Therapies

46: Green Chemistry Strategies for Drug Discovery

47: Fragment-Based Drug Discovery

48: Epigenetics for Drug Discovery

49: New Horizons in Predictive Drug Metabolism and Pharmacokinetics

50: Privileged Scaffolds in Medicinal Chemistry: Design, Synthesis, Evaluation

51: Nanomedicines: Design, Delivery and Detection

52: Synthetic Methods in Drug Discovery: Volume 1

53: Synthetic Methods in Drug Discovery: Volume 2

54: Drug Transporters: Role and Importance in ADME and Drug Development

55: Drug Transporters: Recent Advances and Emerging Technologies

56: Allosterism in Drug Discovery

57: Anti-aging Drugs: From Basic Research to Clinical Practice

58: Antibiotic Drug Discovery: New Targets and Molecular Entities

How to obtain future titles on publication:

A standing order plan is available for this series. A standing order will bring delivery of each new volume immediately on publication.

For further information please contact:

Book Sales Department, Royal Society of Chemistry, Thomas Graham House, Science Park, Milton Road, Cambridge, CB4 0WF, UK

Telephone: +44 (0)1223 420066, Fax: +44 (0)1223 420247,

Visit our website at www.rsc.org/books

Antibiotic Drug Discovery

New Targets and Molecular Entities

Edited by

Steven M. Firestine

Wayne State University, Detriot, USA

and

Troy Lister

Spero Therapeutics, Cambridge, USA

graphic

graphic

Drug Discovery Series No. 58

Print ISBN: 978-1-78262-424-0

PDF eISBN: 978-1-78262-987-0

EPUB eISBN: 978-1-78801-149-5

ISSN: 2041-3203

A catalogue record for this book is available from the British Library

© The Royal Society of Chemistry 2017

All rights reserved

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