Computational Systems Pharmacology and Toxicology
CHAPTER 2: Databases Facilitating Systems Biology Approaches in Toxicology
Published:01 Mar 2017
Special Collection: 2017 ebook collectionSeries: Issues in Toxicology
Dale E. Johnson, Ann M. H. Heslin, 2017. "Databases Facilitating Systems Biology Approaches in Toxicology", Computational Systems Pharmacology and Toxicology, Rudy J Richardson, Dale E Johnson
Download citation file:
The on-going enhancement of information sources and tools to augment the understanding of chemical toxicity in human and environmental systems is a critical aspect of systems toxicology. This chapter highlights multiple free on-line information sources and tools categorized into toxicity-related; chemical–gene–protein interactions; biological pathway–network relationships; chemistry, structural alert, and quantitative structure–activity relationships (QSAR)-related; and drug and drug-target information. These databases and tools represent the latest non-commercial sources for expanded research and safety assessment in toxicology research.