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Drug Discovery
Anti-aging Drugs: From Basic Research to Clinical Practice
Edited by
Alexander M Vaiserman
Alexander M Vaiserman
Institute of Gerontology, Kiev, Ukraine
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Hardback ISBN:
978-1-78262-435-6
PDF ISBN:
978-1-78262-660-2
EPUB ISBN:
978-1-78262-985-6
Special Collection:
2017 ebook collection
Series:
Drug Discovery
No. of Pages:
570
Publication date:
18 Jan 2017
Book Chapter
CHAPTER 17: Antidiabetic Biguanides as Anti-Aging Drugs
By
Vladimir N. Anisimov
Department of Carcinogenesis and Oncogerontology, N.N. Petrov Research Institute of Oncology Leningradskaya str., 68, Pesochny-2 St. Petersburg 197758 Russian Ferderation aging@mail.ru Institute of Cytology, The Russian Academy of Sciences Tikhoretsky prosp. 4 St.Petersburg 194064 Russian Federation People Friendship University of Russia Miklukho-Maklay str. 6 Moscow 117198 Russian Federation
Vladimir N. Anisimov
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Published:18 Jan 2017
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Special Collection: 2017 ebook collectionSeries: Drug Discovery
Citation
Vladimir N. Anisimov, 2017. "Antidiabetic Biguanides as Anti-Aging Drugs", Anti-aging Drugs: From Basic Research to Clinical Practice, Alexander M Vaiserman
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Evidence has emerged that metformin and other antidiabetic biguabides are promising candidates for pharmacological interventions leading to slowing down of aging, prolonged life span and preventing or postponing age-associate diseases, including cancer. In this chapter, the available data on effects of biguanides in rodents are summarized and discussed.
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