Anti-aging Drugs: From Basic Research to Clinical Practice
CHAPTER 20: Short Peptides Regulate Gene Expression, Protein Synthesis and Enhance Life Span
Published:18 Jan 2017
Special Collection: 2017 ebook collectionSeries: Drug Discovery
Vladimir Khavinson, Irina Popovich, 2017. "Short Peptides Regulate Gene Expression, Protein Synthesis and Enhance Life Span", Anti-aging Drugs: From Basic Research to Clinical Practice, Alexander M Vaiserman
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It was shown in different experimental models that short peptides possess anti-carcinogenic and geroprotective properties, while being safe in long-term administration to animals. Experimental studies of complex peptide bioregulators and synthetic peptides suggested major molecular mechanisms of their biological activity and identified specificity of their action. Effects of short peptides on gene expression, proliferation, apoptosis, differentiation and functions of various organs have been studied. These studies motivate application of peptides in old and senile people to maintain and correct major resources of the human organism.