Chemical Biology of Glycoproteins
CHAPTER 10: Chemical Approaches to Image Protein Glycosylation
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Published:20 Mar 2017
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Special Collection: 2017 ebook collectionSeries: Chemical Biology
Wei Lin, Ling Gao, Ke Qin, Xing Chen, 2017. "Chemical Approaches to Image Protein Glycosylation", Chemical Biology of Glycoproteins, Zhongping Tan, Lai-Xi Wang
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Protein glycosylation plays essential roles in regulating physiological activities of proteins. Visualization of protein glycans in living system is invaluable for elucidating the biological functions of protein glycosylation. However, it has proven challenging to develop tools for molecular imaging of glycans. This chapter highlights recently developed chemical tools that enable visualization of protein glycosylation. The development of these chemical methods is introduced in the contexts of important protein glycosylation and imaging tools for visualizing glycans in general.