Sustainable Catalysis: Without Metals or Other Endangered Elements, Part 2
Chapter 15: Nonquaternised Cinchona Alkaloid Derivatives as Asymmetric Organocatalysts for Carbon–Heteroatom Bond-forming Reactions
-
Published:16 Nov 2015
-
Special Collection: 2015 ebook collection , ECCC Environmental eBooks 1968-2022 , 2011-2015 physical chemistry subject collectionSeries: Green Chemistry
Zdenko Hameršak, Irena Dokli, Trpimir Ivšić, 2015. "Nonquaternised Cinchona Alkaloid Derivatives as Asymmetric Organocatalysts for Carbon–Heteroatom Bond-forming Reactions", Sustainable Catalysis: Without Metals or Other Endangered Elements, Part 2, Michael North, Michael North
Download citation file:
Cinchona alkaloids and their derivatives catalyse an astounding variety of synthetically important stereoselective reactions, thus providing access to a huge number of products of high enantiopurity. This chapter covers the use of natural and modified Cinchona alkaloids (quaternised, urea and thiourea derivatives are not included) in carbon–heteroatom bond-forming reactions – specifically: anhydride ring opening, hydrophosphonylation, epoxidations and hydroperoxidations, aziridination, lactone and lactam formation, epoxide and aziridine ring opening, amination, hydroxylation, sulfenylation and halogenation. Asymmetric hetero-Michael (oxa, aza, sulfa) additions catalysed by Cinchona alkaloids are also included.
