NMR in Glycoscience and Glycotechnology
This volume focuses on solution and solid-state NMR of carbohydrates, glycoproteins, glyco-technologies, biomass and related topics. It is estimated that at least 80% of all proteins are glycoproteins. Because of the complexity, heterogeneity and flexibility of the sugar chains, the structural biology approaches for glycoconjugates have been generally avoided. NMR techniques although well established for structural analyses of proteins and nucleic acids, cannot be simply applied to this complex class of biomolecules. Nonetheless, recently developed NMR techniques for carbohydrates open the door to conformational studies of a variety of sugar chains of biological interest. NMR studies on glycans will have significant impact on the development of vaccines, adjuvants, therapeutics, biomarkers and on biomass regeneration.
In this volume, the Editors have collected the most up-to-date NMR applications from experts in the field of carbohydrate NMR spectroscopy. Timely and useful, not only for NMR specialists, it will appeal to researchers in the general field of structural biology, biochemistry and biophysics, molecular and cellular biology and material science.
NMR in Glycoscience and Glycotechnology, The Royal Society of Chemistry, 2017.
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CHAPTER 1: Intramolecular Hydrogen Bonding in Glycans in Aqueous Solutionp1-19ByMarcos D. Battistel;Marcos D. BattistelLaboratory of Bacterial Polysaccharides, Office of Vaccines Research and Review, Center for Biologics, Evaluation and Research, Food and Drug AdministrationSilver SpringMaryland 20903USA[email protected]Search for other works by this author on:Hugo F. Azurmendi;Hugo F. AzurmendiLaboratory of Bacterial Polysaccharides, Office of Vaccines Research and Review, Center for Biologics, Evaluation and Research, Food and Drug AdministrationSilver SpringMaryland 20903USA[email protected]Search for other works by this author on:Darón I. FreedbergDarón I. FreedbergLaboratory of Bacterial Polysaccharides, Office of Vaccines Research and Review, Center for Biologics, Evaluation and Research, Food and Drug AdministrationSilver SpringMaryland 20903USA[email protected]Search for other works by this author on:
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CHAPTER 2: NMR Spin-Couplings in Saccharides: Relationships Between Structure, Conformation and the Magnitudes of JHH, JCH and JCC Valuesp20-100ByMatthew J. Hadad;Matthew J. HadadDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Wenhui Zhang;Wenhui ZhangDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Toby Turney;Toby TurneyDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Luke Sernau;Luke SernauDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Xiaocong Wang;Xiaocong WangComplex Carbohydrate Research Center, University of GeorgiaAthensGA 30602USASearch for other works by this author on:Robert J. Woods;Robert J. WoodsComplex Carbohydrate Research Center, University of GeorgiaAthensGA 30602USASearch for other works by this author on:Andrew Incandela;Andrew IncandelaDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Ivana Surjancev;Ivana SurjancevDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Amy Wang;Amy WangDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Mi-Kyung Yoon;Mi-Kyung YoonDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Atticus Coscia;Atticus CosciaDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Christopher Euell;Christopher EuellDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Reagen Meredith;Reagen MeredithDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:Ian Carmichael;Ian CarmichaelThe Radiation Laboratory, University of Notre DameNotre DameIN 46556-5670USASearch for other works by this author on:Anthony S. SerianniAnthony S. SerianniDepartment of Chemistry and Biochemistry, University of Notre DameNotre DameIN 46556-5670USA[email protected]Search for other works by this author on:
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CHAPTER 3: Insights into Carbohydrate Recognition by 3D Structure Determination of Protein–Carbohydrate Complexes Using NMRp101-122ByMario SchubertMario SchubertSearch for other works by this author on:
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CHAPTER 4: Paramagnetic, RDC and RCSA Constraints in the Structural Analysis of Glycansp123-149ByJames H. Prestegard;James H. PrestegardComplex Carbohydrate Research Center, University of Georgia315 Riverbend RdAthensGeorgia30602USA[email protected]Search for other works by this author on:Alexander EletskyAlexander EletskyComplex Carbohydrate Research Center, University of Georgia315 Riverbend RdAthensGeorgia30602USA[email protected]Search for other works by this author on:
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CHAPTER 5: Lanthanide-Chelating Carbohydrate Conjugates to Detect Carbohydrate–Protein Interactionsp150-160ByAngeles Canales;Angeles CanalesDepartamento de Química Orgánica I, Facultad de Ciencias Químicas, Universidad Complutense de MadridE-28040 MadridSpainSearch for other works by this author on:Jesús Jiménez-BarberoJesús Jiménez-BarberoIkerbasque, Basque Foundation for ScienceBilbaoSpainDepartment of Organic Chemistry II, Faculty of Science & Technology, University of the Basque Country48940 LeioaBizkaiaSpainSearch for other works by this author on:
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CHAPTER 6: NMR Characterization of the Conformations, Dynamics, and Interactions of Glycosphingolipidsp161-178ByMaho Yagi-Utsumi;Maho Yagi-UtsumiOkazaki Institute for Integrative Bioscience and Institute for Molecular Science, National Institutes of Natural SciencesHigashiyama 5-1, MyodaijiOkazaki 444-8787Japan[email protected]Graduate School of Pharmaceutical Sciences, Nagoya City UniversityTanabe-dori 3-1Mizuho-ku, Nagoya 467-8603JapanSearch for other works by this author on:Takumi Yamaguchi;Takumi YamaguchiOkazaki Institute for Integrative Bioscience and Institute for Molecular Science, National Institutes of Natural SciencesHigashiyama 5-1, MyodaijiOkazaki 444-8787Japan[email protected]Graduate School of Pharmaceutical Sciences, Nagoya City UniversityTanabe-dori 3-1Mizuho-ku, Nagoya 467-8603JapanSchool of Materials Science, Japan Advanced Institute of Science and Technology1-1 AsahidaiNomi 923-1292JapanSearch for other works by this author on:Yoshinori Uekusa;Yoshinori UekusaOkazaki Institute for Integrative Bioscience and Institute for Molecular Science, National Institutes of Natural SciencesHigashiyama 5-1, MyodaijiOkazaki 444-8787Japan[email protected]Search for other works by this author on:Koichi KatoKoichi KatoOkazaki Institute for Integrative Bioscience and Institute for Molecular Science, National Institutes of Natural SciencesHigashiyama 5-1, MyodaijiOkazaki 444-8787Japan[email protected]Graduate School of Pharmaceutical Sciences, Nagoya City UniversityTanabe-dori 3-1Mizuho-ku, Nagoya 467-8603JapanSearch for other works by this author on:
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CHAPTER 7: NMR Analysis of Glycosyltransferasesp179-193ByThomas PetersThomas PetersUniversity of Lübeck, Institute of ChemistryRatzeburger Allee 16023562 LübeckGermany[email protected]Search for other works by this author on:
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CHAPTER 8: Stable Isotope Labeling of Glycoproteins for NMR Studyp194-207ByYoshiki Yamaguchi;Yoshiki YamaguchiStructural Glycobiology Team, Systems Glycobiology Research Group, RIKEN-Max Planck Joint Research Center, RIKEN Global Research Cluster2-1 HirosawaWako, Saitama 351-0198Japan[email protected]Search for other works by this author on:Hirokazu Yagi;Hirokazu YagiGraduate School of Pharmaceutical Sciences, Nagoya City University3-1 Tanabe-doriMizuho-ku, Nagoya467-8603JapanSearch for other works by this author on:Koichi KatoKoichi KatoGraduate School of Pharmaceutical Sciences, Nagoya City University3-1 Tanabe-doriMizuho-ku, Nagoya467-8603JapanInstitute for Molecular Science and Okazaki Institute for Integrative Bioscience, National Institutes of National Sciences5-1 Higashimaya MyodaijiOkazaki 444-8787JapanSearch for other works by this author on:
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CHAPTER 9: Quantifying Carbohydrate Motions Through Solution Measurements: Applications to Immunoglobulin G Fcp208-227ByAdam W. BarbAdam W. BarbRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State UniversityAmesIA 50011USA[email protected]Search for other works by this author on:
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CHAPTER 10: Analysis of Glycosaminoglycans by 15N-NMR Spectroscopyp228-249ByVitor H. PominVitor H. PominProgram of Glycobiology, Institute of Medical Biochemistry Leopoldo de Meis, University Hospital Clementino Fraga Filho, Federal University of Rio de JaneiroRio de JaneiroRJ, 21941-913Brazil[email protected][email protected][email protected]Complex Carbohydrate Research Center, University of GeorgiaAthens, 30602United States of AmericaSearch for other works by this author on:
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CHAPTER 11: NMR Studies of Protein–Glycosaminoglycan Interactionsp250-268ByXu WangXu WangSearch for other works by this author on:
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CHAPTER 12: Solid-State NMR Analysis of Mannose Recognition by Pradimicin Ap269-289ByYu Nakagawa;Yu NakagawaDepartment of Applied Molecular Biosciences, Graduate School of Bioagricultural Sciences, Nagoya UniversityFuro-cho, Chikusa-kuNagoya 464-8601JapanSynthetic Cellular Chemistry Laboratory, RIKEN2-1 Hirosawa, WakoSaitama 351-0198Japan[email protected]Search for other works by this author on:Yukishige ItoYukishige ItoSynthetic Cellular Chemistry Laboratory, RIKEN2-1 Hirosawa, WakoSaitama 351-0198Japan[email protected]Search for other works by this author on:
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CHAPTER 13: Structure and Dynamics of Polysaccharides in Plant Cell Walls from Solid-State NMRp290-304ByTuo Wang;Tuo WangDepartment of Chemistry, Massachusetts Institute of Technology170 Albany StreetCambridgeMA 02139USA[email protected]Search for other works by this author on:Mei HongMei HongDepartment of Chemistry, Massachusetts Institute of Technology170 Albany StreetCambridgeMA 02139USA[email protected]Search for other works by this author on:
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CHAPTER 14: New Methods for the Analysis of Heterogeneous Polysaccharides – Lessons Learned from the Heparin Crisisp305-334ByTimothy R. Rudd;Timothy R. RuddNational Institute for Biological Standards and ControlBlanche Lane, South MimmsPotters BarHertfordshireEN6 3QG UK[email protected]Search for other works by this author on:Edwin A. Yates;Edwin A. YatesDepartment of Biochemistry, Institute of Integrative Biology, University of LiverpoolCrown StreetLiverpoolL69 7ZB UK[email protected]Search for other works by this author on:Marco GuerriniMarco GuerriniIstituto di Ricerche Chimiche e Biochimiche ″G. Ronzoni″Via Giuseppe Colombo 81Milano20133 Italy[email protected]Search for other works by this author on:
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CHAPTER 15: NMR Chemical Shift Predictions and Structural Elucidation of Oligo- and Polysaccharides by the Computer Program CASPERp335-352ByJonas Ståhle;Jonas StåhleDepartment of Organic Chemistry, Arrhenius Laboratory, Stockholm UniversityS-106 91 StockholmSweden[email protected]Search for other works by this author on:Göran WidmalmGöran WidmalmDepartment of Organic Chemistry, Arrhenius Laboratory, Stockholm UniversityS-106 91 StockholmSweden[email protected]Search for other works by this author on:
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CHAPTER 16: NMR Databases for Plant Cell Wall Biopolymersp353-368ByWilliam S. York;William S. YorkUniversity of Georgia, Complex Carbohydrate Research Center315 Riverbend RoadAthensGA 30602USA[email protected]Search for other works by this author on:Mehdi Allahyari;Mehdi AllahyariUniversity of Georgia, Department of Computer Science, 415 Boyd Graduate Studies Research CenterAthensGA 30602USASearch for other works by this author on:John D. HoganJohn D. HoganBoston University School of Medicine670 Albany St., Suite 504BostonMA 02118USASearch for other works by this author on:
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CHAPTER 17: Polysaccharides as Major Carbon Sources in Environmental Biodiversityp369-395ByJun Kikuchi;Jun KikuchiRIKEN Center for Sustainable Resource Science1-7-22 Suehiro-cho, Tsurumi-kuYokohamaKanagawa 230-0045JapanGraduate School of Medical Life Science, Yokohama City University1-7-29 Suehiro-cho, Tsurumi-kuYokohamaKanagawa 230-0045JapanGraduate School of Bioagricultural Sciences, Nagoya University1 Furo-cho, Chikusa-kuNagoyaAichi 464-0810Japan[email protected]Search for other works by this author on:Takanori KomatsuTakanori KomatsuRIKEN Center for Sustainable Resource Science1-7-22 Suehiro-cho, Tsurumi-kuYokohamaKanagawa 230-0045JapanGraduate School of Medical Life Science, Yokohama City University1-7-29 Suehiro-cho, Tsurumi-kuYokohamaKanagawa 230-0045JapanSearch for other works by this author on:
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