Skip to Main Content
Skip Nav Destination

In the study of glycoproteins by NMR spectroscopy, stable isotope labeling is a challenging but important step. Labeling by metabolic means is useful, but choice of production vehicles (mammalian or non-mammalian expression systems) and of medium (or diet) are critical for obtaining functional glycoproteins with high isotope enrichment and with the appropriate glycoform framework. Metabolic labeling coupled with in vitro enzymatic reactions enables remodeling or modification of the NMR target glycoform. This chapter outlines recent progress in isotope labeling techniques of glycoproteins using mammalian and non-mammalian expression systems.

You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Don't already have an account? Register
Close Modal

or Create an Account

Close Modal
Close Modal