Modern Biocatalysis: Advances Towards Synthetic Biological Systems
The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.
Modern Biocatalysis: Advances Towards Synthetic Biological Systems, The Royal Society of Chemistry, 2018.
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Chapter 1: Genome Mining for Enzyme Discoveryp1-27ByAnne Zaparucha;Anne ZaparuchaGénomique MétaboliqueGenoscope, Institut François Jacob, CEA CNRS, Univ Evry, Univ Paris-Saclay91057 EvryFrance[email protected]Search for other works by this author on:Véronique de Berardinis;Véronique de BerardinisGénomique MétaboliqueGenoscope, Institut François Jacob, CEA CNRS, Univ Evry, Univ Paris-Saclay91057 EvryFrance[email protected]Search for other works by this author on:Carine Vaxelaire-VergneCarine Vaxelaire-VergneGénomique MétaboliqueGenoscope, Institut François Jacob, CEA CNRS, Univ Evry, Univ Paris-Saclay91057 EvryFrance[email protected]Search for other works by this author on:
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Chapter 2: Exploiting Natural Diversity for Industrial Enzymatic Applicationsp28-52ByYasuhisa Asano;Yasuhisa AsanoBiotechnology Research Center and Department of Biotechnology, Toyama Prefectural University5180 KurokawaImizuToyama939-0398Japan[email protected]Asano Active Enzyme Molecule Project, ERATO, JST5180 KurokawaImizuToyama939-0398JapanSearch for other works by this author on:Richard MetznerRichard MetznerBiotechnology Research Center and Department of Biotechnology, Toyama Prefectural University5180 KurokawaImizuToyama939-0398Japan[email protected]Asano Active Enzyme Molecule Project, ERATO, JST5180 KurokawaImizuToyama939-0398JapanSearch for other works by this author on:
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Chapter 3: Artificial Metalloenzymesp53-87ByJean-Pierre Mahy;Jean-Pierre MahyInstitut de Chimie Moléculaire et des Matériaux, UMR 8182, Laboratoire de Chimie Organique et Bioinorganique, Université Paris-Saclay, Université Paris-Sud, CNRS91405Orsay CedexFrance[email protected]Search for other works by this author on:Wadih Ghattas;Wadih GhattasInstitut de Chimie Moléculaire et des Matériaux, UMR 8182, Laboratoire de Chimie Organique et Bioinorganique, Université Paris-Saclay, Université Paris-Sud, CNRS91405Orsay CedexFrance[email protected]Search for other works by this author on:Thibault Di Méo;Thibault Di MéoInstitut de Chimie Moléculaire et des Matériaux, UMR 8182, Laboratoire de Chimie Organique et Bioinorganique, Université Paris-Saclay, Université Paris-Sud, CNRS91405Orsay CedexFrance[email protected]Institut de Biologie Intégrative de la Cellule, UMR 9198, Laboratoire de Modélisation et Ingénierie des Protéines, Université Paris-Saclay, Université Paris-Sud, CNRS91405Orsay CedexFranceSearch for other works by this author on:Rémy RicouxRémy RicouxInstitut de Chimie Moléculaire et des Matériaux, UMR 8182, Laboratoire de Chimie Organique et Bioinorganique, Université Paris-Saclay, Université Paris-Sud, CNRS91405Orsay CedexFrance[email protected]Search for other works by this author on:
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Chapter 4: Computational Enzyme Design: Successes, Challenges, and Future Directionsp88-116ByAntony D. St-Jacques;Antony D. St-JacquesDepartment of Chemistry and Biomolecular Sciences, University of Ottawa10 Marie-CurieOttawaOntario K1N 6N5Canada[email protected]Centre for Catalysis Research and Innovation, University of Ottawa30 Marie-CurieOttawaOntario K1N 6N5CanadaSearch for other works by this author on:Olivier Gagnon;Olivier GagnonDepartment of Chemistry and Biomolecular Sciences, University of Ottawa10 Marie-CurieOttawaOntario K1N 6N5Canada[email protected]Centre for Catalysis Research and Innovation, University of Ottawa30 Marie-CurieOttawaOntario K1N 6N5CanadaSearch for other works by this author on:Roberto A. ChicaRoberto A. ChicaDepartment of Chemistry and Biomolecular Sciences, University of Ottawa10 Marie-CurieOttawaOntario K1N 6N5Canada[email protected]Centre for Catalysis Research and Innovation, University of Ottawa30 Marie-CurieOttawaOntario K1N 6N5CanadaSearch for other works by this author on:
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Chapter 5: Computational Techniques for Efficient Biocatalysisp117-152ByIonnis V. Pavlidis;Ionnis V. PavlidisUniversity of Crete, Department of Chemistry, Enzyme Technology LaboratoryVoutes University CampusHeraklion, 70013GreeceSearch for other works by this author on:Natalie M. Hendrikse;Natalie M. HendrikseKTH Royal Institute of Technology, School of Chemical Science and EngineeringTeknikringen 30Stockholm, 100 44Sweden[email protected]KTH Royal Institute of Technology, Science for Life LaboratoryTomtebodavägen 23Solna, 171 65SwedenSearch for other works by this author on:Per-Olof SyrénPer-Olof SyrénKTH Royal Institute of Technology, School of Chemical Science and EngineeringTeknikringen 30Stockholm, 100 44Sweden[email protected]KTH Royal Institute of Technology, Science for Life LaboratoryTomtebodavägen 23Solna, 171 65SwedenSearch for other works by this author on:
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Chapter 6: Modulating Enzyme Activity via Incorporation of Non-canonical Amino Acidsp153-177ByJules Kirk;Jules KirkResearch School of Chemistry, Australian National UniversityCanberra, ACT 2601Australia[email protected]Search for other works by this author on:Thomas Huber;Thomas HuberResearch School of Chemistry, Australian National UniversityCanberra, ACT 2601Australia[email protected]Search for other works by this author on:Colin J. JacksonColin J. JacksonResearch School of Chemistry, Australian National UniversityCanberra, ACT 2601Australia[email protected]Search for other works by this author on:
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Chapter 7: Enhancing Enzymatic Performance via Restricted Sequence Space Approachesp178-202ByAndreas S. Bommarius;Andreas S. BommariusSchool of Chemical and Biomolecular Engineering, Georgia Institute of TechnologyAtlantaGA 30332USASchool of Chemistry and Biochemistry, Georgia Institute of TechnologyAtlantaGA 30332USA[email protected]Search for other works by this author on:Bettina R. BommariusBettina R. BommariusSchool of Chemical and Biomolecular Engineering, Georgia Institute of TechnologyAtlantaGA 30332USASearch for other works by this author on:
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Chapter 8: Customizing Transcription-factor Biosensors for Modern Biotechnologyp203-233ByGavin J. WilliamsGavin J. WilliamsComparative Medicine Institute, NC State UniversityRaleighNCUSASearch for other works by this author on:
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Chapter 9: Exploiting Biosynthetic Pathways in Fungi: Opportunities for Enhanced or Novel Productionp234-260ByKate M. J. de Mattos-Shipley;Kate M. J. de Mattos-ShipleySchool of Biological Sciences, University of Bristol24 Tyndall AvenueBristol BS8 1TQUK[email protected]Search for other works by this author on:Andy M. BaileyAndy M. BaileySchool of Biological Sciences, University of Bristol24 Tyndall AvenueBristol BS8 1TQUK[email protected]Search for other works by this author on:
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Chapter 10: Engineering Enzymes for Natural Product Biosynthesis and Diversificationp261-286ByFrederick Twigg;Frederick TwiggUniversity of California, Berkeley, Department of Chemical and Biomolecular Engineering2151 Berkeley WayBerkeleyCA 94720USA[email protected]Search for other works by this author on:David Skyrud;David SkyrudUniversity of California, Berkeley, Department of Chemistry2151 Berkeley WayBerkeleyCA 94720USASearch for other works by this author on:Jeffrey Li;Jeffrey LiUniversity of California, Berkeley, Department of Chemical and Biomolecular Engineering2151 Berkeley WayBerkeleyCA 94720USA[email protected]Search for other works by this author on:Wenjun ZhangWenjun ZhangUniversity of California, Berkeley, Department of Chemical and Biomolecular Engineering2151 Berkeley WayBerkeleyCA 94720USA[email protected]Search for other works by this author on:
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Chapter 11: Impact of Synthetic Biology on Secondary Metabolite Biosynthesisp287-320ByFredarla S. Miller;Fredarla S. MillerDepartment of Biochemistry, Molecular Biology, and Biophysics & BioTechnology Institute, University of Minnesota-Twin CitiesSt. PaulMN 55108USA[email protected]Search for other works by this author on:Michael F. FreemanMichael F. FreemanDepartment of Biochemistry, Molecular Biology, and Biophysics & BioTechnology Institute, University of Minnesota-Twin CitiesSt. PaulMN 55108USA[email protected]Search for other works by this author on:
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Chapter 12: Self-contained Biocatalystsp321-350ByJon D. StewartJon D. StewartUniversity of Florida, Department of ChemistryP.O. Box 117200GainesvilleFL 32611USA[email protected]Search for other works by this author on:
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Chapter 13: Designing Multi-enzymatic Systems for the Preparation of Optically Active Moleculesp351-386ByLía Martínez-Montero;Lía Martínez-MonteroDepartment of Organic and Inorganic Chemistry, Biotechnology Institute of Asturias, University of OviedoAvenida Julián ClaveríaOviedo 33006Spain[email protected]Search for other works by this author on:Iván LavanderaIván LavanderaDepartment of Organic and Inorganic Chemistry, Biotechnology Institute of Asturias, University of OviedoAvenida Julián ClaveríaOviedo 33006Spain[email protected]Search for other works by this author on:
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Chapter 14: Artificial Biocatalytic Cascades to Alcohols and Aminesp387-438ByJoerg H. Schrittwieser;Joerg H. SchrittwieserInstitute of Chemistry, Organic and Bioorganic Chemistry, University of GrazNAWI Graz, BioTechMed Graz, Heinrichstrasse 288010 GrazAustria[email protected][email protected]Search for other works by this author on:Stefan Velikogne;Stefan VelikogneACIB GmbH, c/o Department of Chemistry, University of GrazHeinrichstrasse 288010 GrazAustriaSearch for other works by this author on:Wolfgang KroutilWolfgang KroutilInstitute of Chemistry, Organic and Bioorganic Chemistry, University of GrazNAWI Graz, BioTechMed Graz, Heinrichstrasse 288010 GrazAustria[email protected][email protected]ACIB GmbH, c/o Department of Chemistry, University of GrazHeinrichstrasse 288010 GrazAustriaSearch for other works by this author on:
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Chapter 15: Emerging Fields in One-pot Multi-step Synthesis with Combined Chemo- and Bio-catalysts: Sequential- and Domino-type Process Concepts as well as Compartmentation Strategiesp439-472ByHarald GrögerHarald GrögerChair of Organic Chemistry I, Faculty of Chemistry, Bielefeld UniversityUniversitätsstr. 2533615 BielefeldGermany[email protected]Search for other works by this author on:
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Chapter 16: Technical Biocatalysisp473-515ByAndrés Illanes;Andrés IllanesSchool of Biochemical Engineering, Pontificia Universidad Católica de ValparaísoAvenida Brasil 20852340000 ValparaísoChile[email protected]Search for other works by this author on:Lorena Wilson;Lorena WilsonSchool of Biochemical Engineering, Pontificia Universidad Católica de ValparaísoAvenida Brasil 20852340000 ValparaísoChile[email protected]Search for other works by this author on:Carlos VeraCarlos VeraSchool of Biochemical Engineering, Pontificia Universidad Católica de ValparaísoAvenida Brasil 20852340000 ValparaísoChile[email protected]Search for other works by this author on:
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Chapter 17: Biocatalytic Process Engineeringp516-538ByJohn M. WoodleyJohn M. WoodleyDepartment of Chemical and Biochemical Engineering, Technical University of Denmark (DTU)DK-2800 LyngbyDenmark[email protected]Search for other works by this author on:
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Chapter 18: Enzymes for Detection and Decontamination of Chemical Warfare Agentsp539-565ByZbynek Prokop;Zbynek ProkopInternational Clinical Research Center, St. Anne's University Hospital BrnoPekarska 53656 91 BrnoCzech Republic[email protected]Enantis, s.r.o.Kamenice 34625 00 BrnoCzech RepublicSearch for other works by this author on:Tana Koudelakova;Tana KoudelakovaInternational Clinical Research Center, St. Anne's University Hospital BrnoPekarska 53656 91 BrnoCzech Republic[email protected]Search for other works by this author on:Sarka Bidmanova;Sarka BidmanovaInternational Clinical Research Center, St. Anne's University Hospital BrnoPekarska 53656 91 BrnoCzech Republic[email protected]Search for other works by this author on:Jiri DamborskyJiri DamborskyInternational Clinical Research Center, St. Anne's University Hospital BrnoPekarska 53656 91 BrnoCzech Republic[email protected]Enantis, s.r.o.Kamenice 34625 00 BrnoCzech RepublicSearch for other works by this author on:
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