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New Developments in NMR
Contrast Agents for MRI: Experimental Methods
Edited by
Valérie C Pierre;
Valérie C Pierre
University of Minnesota, USA
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Matthew J Allen
Matthew J Allen
Wayne State University, USA
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Hardback ISBN:
978-1-78262-447-9
PDF ISBN:
978-1-78801-014-6
EPUB ISBN:
978-1-78801-254-6
Special Collection:
2017 ebook collection
Series:
New Developments in NMR
No. of Pages:
598
Publication date:
09 Nov 2017
Book Chapter
Chapter 6: Fluorine-based Contrast Agents
By
Paula Foster
;
Paula Foster
Robarts Research Institute, University of Western Ontario
London
Ontario
N6A 3K7
Canada
Department of Medical Biophysics, University of Western Ontario
London
Ontario
N6A 3K7
Canada
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Alex Li
;
Alex Li
Robarts Research Institute, University of Western Ontario
London
Ontario
N6A 3K7
Canada
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Robert Bartha
Robert Bartha
Robarts Research Institute, University of Western Ontario
London
Ontario
N6A 3K7
Canada
Department of Medical Biophysics, University of Western Ontario
London
Ontario
N6A 3K7
Canada
Departments of Medical Imaging and Psychiatry, University of Western Ontario
London
Ontario
N6A 3K7
Canada
[email protected]
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Published:09 Nov 2017
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Special Collection: 2017 ebook collectionSeries: New Developments in NMR
Page range:
479 - 498
Citation
E. Stares, J. Rho, E. T. Ahrens, P. Foster, A. Li, and R. Bartha, in Contrast Agents for MRI: Experimental Methods, ed. V. C. Pierre and M. J. Allen, The Royal Society of Chemistry, 2017, ch. 6, pp. 479-498.
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This chapter focuses on fluorine-based probes and pays particular attention to their use for cell tracking with MRI. Most of these probes incorporate perfluorocarbon molecules that are formulated as colloidal suspensions or emulsions in aqueous buffer. A discussion on the design of fluorine probes and emulsions is followed by a description of the acquisition of 19F MRI phantoms.
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