Sustainable Synthesis of Pharmaceuticals: Using Transition Metal Complexes as Catalysts
There is a growing interest in the development of sustainable processes for the synthesis of pharmaceuticals and this book bridges the divide between industrial examples and the fundamental chemistry. It explains the basic principles of using transition metal catalysis with several green approaches for the synthesis of pharmaceuticals. The topic is an important one for green chemistry and the chapters in this book on hydroformylation, green oxidation and olefin metathesis will also be of interest to both medicinal and organic chemists.
Written by leading experts in the field, it provides a valuable and easy tool for scientists and industrialists who require information regarding this topic.
Sustainable Synthesis of Pharmaceuticals: Using Transition Metal Complexes as Catalysts, The Royal Society of Chemistry, 2018.
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Table of contents
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Chapter 1: Introductionp1-4ByM. M. Pereira;M. M. PereiraUniversity of Coimbra, CQC, Department of ChemistryRua LargaCoimbra 3004-535Portugal[email protected][email protected]Search for other works by this author on:M. J. F. CalveteM. J. F. CalveteUniversity of Coimbra, CQC, Department of ChemistryRua LargaCoimbra 3004-535Portugal[email protected][email protected]Search for other works by this author on:
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Chapter 2: Transition Metals in Greener Pharmaceutical Chemistryp5-7ByJ. H. ClarkJ. H. ClarkSearch for other works by this author on:
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Chapter 3: Sustainable Synthesis of Pharmaceuticals Using Alternative Techniques: Microwave, Sonochemistry and Mechanochemistryp8-39ByM. Pineiro;M. PineiroUniversity of Coimbra, CQC, Department of ChemistryRuaLargaCoimbra 3004-535Portugal[email protected]Search for other works by this author on:M. J. F. CalveteM. J. F. CalveteUniversity of Coimbra, CQC, Department of ChemistryRuaLargaCoimbra 3004-535Portugal[email protected]Search for other works by this author on:
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Chapter 4: Carbonylation Reactions in the Synthesis of Pharmaceutically Active Compoundsp40-65ByR. Skoda-Földes;R. Skoda-FöldesUniversity of Pannonia, Department of Organic ChemistryEgyetem. u. 10.Veszprém 8200Hungary[email protected]Search for other works by this author on:L. KollárL. KollárUniversity of Pécs, Department of Inorganic Chemistry and MTA-PTE Research Group for Selective Chemical SynthesesIfjúság u. 6.7624 PécsHungarySearch for other works by this author on:
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Chapter 5: Applications of Catalytic Hydroformylation in the Synthesis of Biologically Relevant Synthons and Drugsp66-104ByM. M. PereiraM. M. PereiraSearch for other works by this author on:
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Chapter 6: Transfer Hydrogenation with Non-toxic Metals for Drug Synthesisp105-138ByB. RoyoB. RoyoITQB NOVA, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de LisboaAv. da República2780-157 OeirasPortugal[email protected]Search for other works by this author on:
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Chapter 7: Green Metal-catalysed Synthesis of Pharmaceutically Useful Asymmetric Epoxides and Sulfoxidesp139-192ByC. C. RomãoC. C. RomãoSearch for other works by this author on:
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Chapter 8: C–C Bond Formation in the Sustainable Synthesis of Pharmaceuticalsp193-229ByL. M. D. R. S. Martins;L. M. D. R. S. MartinsUniversidade de Lisboa, Centro de Química Estrutural, Instituto Superior TécnicoAv. Rovisco Pais1049-001 LisboaPortugal[email protected]Search for other works by this author on:A. M. F. Phillips;A. M. F. PhillipsUniversidade de Lisboa, Centro de Química Estrutural, Instituto Superior TécnicoAv. Rovisco Pais1049-001 LisboaPortugal[email protected]Search for other works by this author on:A. J. L. PombeiroA. J. L. PombeiroUniversidade de Lisboa, Centro de Química Estrutural, Instituto Superior TécnicoAv. Rovisco Pais1049-001 LisboaPortugal[email protected]Search for other works by this author on:
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Chapter 9: Metal-catalysed Metathesis Reactions for Greener Synthon/Drug Synthesisp230-252ByE. N. dos Santos;E. N. dos SantosUniversidade Federal de Minas Gerais, Departamento de Química-ICExAv. Antônio Carlos 6627Belo Horizonte 31270-901Brazil[email protected]Search for other works by this author on:A. V. Granato;A. V. GranatoUniversidade Federal de Minas Gerais, Departamento de Química-ICExAv. Antônio Carlos 6627Belo Horizonte 31270-901Brazil[email protected]Search for other works by this author on:A. G. SantosA. G. SantosUniversidade Federal de Minas Gerais, Departamento de Química-ICExAv. Antônio Carlos 6627Belo Horizonte 31270-901Brazil[email protected]Search for other works by this author on:
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Chapter 10: Tetravalent Boron-based Therapeuticsp253-281ByM. G. H. VicenteM. G. H. VicenteSearch for other works by this author on:
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