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Polyester based thermogelling systems are biocompatible and biodegradable and the sol-to-gel transition can be tuned to body temperature. These properties are ideal for the development of injectable slow-release drug delivery systems and tissue engineering scaffolds. In this chapter, the most recent developments in this class of soft materials are summarized with respect to different types of polyester materials and the correlation of their structures with improvements in gel function for biomedical applications.

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