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Drug Discovery
Acute Brain Impairment: Scientific Discoveries and Translational Research
Edited by
Philip V Peplow;
Philip V Peplow
University of Otago, New Zealand
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Svetlana A Dambinova;
Svetlana A Dambinova
Kennesaw State University
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Thomas A Gennarelli;
Thomas A Gennarelli
George Washington University, USA
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Bridget Martinez
Bridget Martinez
University of California, Merced, USA
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Hardback ISBN:
978-1-78262-950-4
PDF ISBN:
978-1-78801-253-9
EPUB ISBN:
978-1-78801-337-6
Special Collection:
2017 ebook collection
Series:
Drug Discovery
No. of Pages:
348
Publication date:
17 Nov 2017
Book Chapter
Chapter 18: Development of Novel Test Platforms for the Assessment of Brain Injury
By
Richard Baldwin
;
Richard Baldwin
Nanocomposix
San Diego
CA
USA
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Steven J. Oldenburg
Steven J. Oldenburg
Nanocomposix
San Diego
CA
USA
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Published:17 Nov 2017
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Special Collection: 2017 ebook collectionSeries: Drug Discovery
Page range:
315 - 326
Citation
G. A. Izykenova, R. Baldwin, and S. J. Oldenburg, in Acute Brain Impairment
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The development of successful laboratory testing directed towards the identification of brain biomarkers in biological fluids is presented in this chapter. Highlighted is a roadmap for immunoassays measuring antigens–peptides and antibodies to assess brain injury. The choice of unique reagents, assay design, and platform is described in order to build laboratory and point-of-care tests with high performance characteristics.
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