Paramagnetism in Experimental Biomolecular NMR
Paramagnetic NMR is a growing technique that represents an increasingly important tool for the investigation of biomolecules. This book presents an update and overview of the paramagnetic NMR phenomena and effects as well as guidelines for practical implementation of state-of-the-art experiments. All experiments are supported by a solid theoretical foundation. Areas mentioned are the development of solid state NMR, the use of paramagnetic tags providing information on the structure and mobility of the investigated systems, and dynamic nuclear polarization to increase sensitivity.
Compiled by experts in the field, this book has international appeal for researchers as well as students interested in magnetic resonance and structural biology who require experimental support and accessible information.
Paramagnetism in Experimental Biomolecular NMR, The Royal Society of Chemistry, 2018.
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Table of contents
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Chapter 1: NMR Consequences of the Nucleus–Electron Spin Interactionsp1-41ByGiacomo Parigi;Giacomo ParigiDepartment of Chemistry “Ugo Schiff”, University of Florencevia della Lastruccia 3Sesto Fiorentino 50019ItalySearch for other works by this author on:Claudio LuchinatClaudio LuchinatDepartment of Chemistry “Ugo Schiff”, University of Florencevia della Lastruccia 3Sesto Fiorentino 50019ItalySearch for other works by this author on:
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Chapter 2: Intrinsic and Extrinsic Paramagnetic Probesp42-84ByChristoph Nitsche;Christoph NitscheResearch School of Chemistry, Australian National UniversityCanberraACT 2601Australia[email protected]Search for other works by this author on:Gottfried OttingGottfried OttingResearch School of Chemistry, Australian National UniversityCanberraACT 2601Australia[email protected]Search for other works by this author on:
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Chapter 3: Structural and Dynamic Characterization of Protein Domains using Paramagnetic Datap85-106ByMonique J. RogalsMonique J. RogalsSearch for other works by this author on:
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Chapter 4: Treating Biomacromolecular Conformational Variabilityp107-133ByWitold Andrałojć;Witold AndrałojćPolish Academy of Sciences, Institute of Bioorganic ChemistryNoskowskiego 12/14Poznan 61-704PolandSearch for other works by this author on:Enrico RaveraEnrico RaveraUniversity of Florence, Department of Chemistry and Magnetic Resonance CenterVia L. Sacconi 650019 Sesto Fiorentino (FI)Italy[email protected]Search for other works by this author on:
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Chapter 5: Protein–Protein Interactionsp134-162ByMarcellus Ubbink;Marcellus UbbinkLeiden University, Institute of ChemistryEinsteinweg 552333 CC LeidenThe Netherlands[email protected]Search for other works by this author on:Antonella Di SavinoAntonella Di SavinoLeiden University, Institute of ChemistryEinsteinweg 552333 CC LeidenThe Netherlands[email protected]Search for other works by this author on:
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Chapter 6: Solid-state NMR of Paramagnetic Proteinsp163-188ByAndrea Bertarello;Andrea BertarelloCentre de RMN à Très Hauts Champs, Institut des Sciences Analytiques (CNRS, ENS Lyon, UCB Lyon 1), Université de Lyon69100 VilleurbanneFrance[email protected]Search for other works by this author on:Guido PintacudaGuido PintacudaCentre de RMN à Très Hauts Champs, Institut des Sciences Analytiques (CNRS, ENS Lyon, UCB Lyon 1), Université de Lyon69100 VilleurbanneFrance[email protected]Search for other works by this author on:
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Chapter 7: Relaxometry and Contrast Agentsp189-218BySilvio Aime;Silvio AimeTurin University, Department of Molecular Biotechnologies and Health ScienceVia NIzza 52Torino I-10126Italy[email protected]Search for other works by this author on:Eliana Gianolio;Eliana GianolioTurin University, Department of Molecular Biotechnologies and Health ScienceVia NIzza 52Torino I-10126Italy[email protected]Search for other works by this author on:Alessandra VialeAlessandra VialeTurin University, Department of Molecular Biotechnologies and Health ScienceVia NIzza 52Torino I-10126Italy[email protected]Search for other works by this author on:
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Chapter 8: Dynamic Nuclear Polarizationp219-257ByBjörn CorziliusBjörn CorziliusInstitute of Physical and Theoretical Chemistry, Institute of Biophysical Chemistry, and Center for Biomolecular Magnetic Resonance (BMRZ), Goethe University Frankfurt am MainMax-von-Laue-Str. 7-960438 FrankfurtGermany[email protected]Search for other works by this author on:
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Chapter 9: Paramagnetic NMR in Drug Discoveryp258-282ByErhan C. Cetiner;Erhan C. CetinerGoethe Universität Frankfurt am Main, Institute für Organische Chemie und Chemische BiologieMax-von-Laue-Straßig;e 7Frankfurt am Main D-60438Germany[email protected]Search for other works by this author on:Harald SchwalbeHarald SchwalbeGoethe Universität Frankfurt am Main, Institute für Organische Chemie und Chemische BiologieMax-von-Laue-Straßig;e 7Frankfurt am Main D-60438Germany[email protected]Search for other works by this author on:
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Chapter 10: Small Paramagnetic Co-solute Moleculesp283-309ByTobias Madl;Tobias MadlMedical University of Graz, Institute of Molecular Biology and BiochemistryNeue Stiftingtalstrasse 6Graz 8010Austria[email protected][email protected]Search for other works by this author on:Frans A. A. MulderFrans A. A. MulderAarhus University, Department of Chemistry and Interdisciplinary Nanoscience Centre (iNANO)Gustav Wieds Vej 148000 AarhusDenmarkSearch for other works by this author on:
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