Chapter 6: Solid-state NMR of Paramagnetic Proteins
Published:03 Aug 2018
A. Bertarello and G. Pintacuda, in Paramagnetism in Experimental Biomolecular NMR, ed. C. Luchinat, G. Parigi, and E. Ravera, The Royal Society of Chemistry, 2018, ch. 6, pp. 163-188.
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In this chapter we will briefly summarize how the presence of paramagnetic centers affects the NMR properties of paramagnetic proteins in the solid state and describe how the experimental strategies used in solution should be modified to characterize these systems. In parallel, we will provide some case studies from the recent literature that highlight the tremendous potential of solid-state NMR for the characterization of paramagnetic proteins.