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Materials that interact with light and subsequently change their physicochemical properties are of great interest for drug delivery. The human body is semitransparent to light of the near-infrared (NIR) region, which makes it possible to use light as an external stimulus to trigger drug release. In this chapter, we review light-triggered drug release systems of both photochemical and photothermal mechanisms. We explore recent literature on a variety of light-responsive materials for drug delivery, including organic, inorganic, and hybrid systems, which collectively embody the strategies for synergizing light responsiveness for controlled drug release/activation with other drug delivery techniques.

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