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Comprehensive Series in Photochemical & Photobiological Sciences
Cutaneous Photoaging
Edited by
Rachel E B Watson;
Rachel E B Watson
University of Manchester, UK
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Christopher E M Griffiths
Christopher E M Griffiths
University of Manchester, UK
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Hardback ISBN:
978-1-78801-126-6
PDF ISBN:
978-1-78801-598-1
EPUB ISBN:
978-1-78801-860-9
Special Collection:
2019 ebook collection
No. of Pages:
395
Published online:
14 Aug 2019
Published in print:
22 Aug 2019
Book Chapter
CHAPTER 13: Topical Retinoids for the Treatment of Photoaged Skin
By
Elisabeth Schuler Pedersen
;
Elisabeth Schuler Pedersen
University of Michigan, Department of Dermatology
1910 Taubman Center, SPC 5314, 1500 E. Medical Center Dr.
Ann Arbor
MI 48109-5314
USA
[email protected]
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John J. Voorhees
;
John J. Voorhees
University of Michigan, Department of Dermatology
1910 Taubman Center, SPC 5314, 1500 E. Medical Center Dr.
Ann Arbor
MI 48109-5314
USA
[email protected]
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Dana L. Sachs
Dana L. Sachs
University of Michigan, Department of Dermatology
1910 Taubman Center, SPC 5314, 1500 E. Medical Center Dr.
Ann Arbor
MI 48109-5314
USA
[email protected]
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Published:14 Aug 2019
-
Special Collection: 2019 ebook collection
Page range:
341 - 362
Citation
E. S. Pedersen, J. J. Voorhees, and D. L. Sachs, in Cutaneous Photoaging, ed. R. E. B. Watson and C. E. M. Griffiths, The Royal Society of Chemistry, 2019, pp. 341-362.
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Skin photoaging is characterized by fine and coarse wrinkles, dyspigmentation and textural irregularities. These clinical findings have negative cosmetic and functional implications. Topical retinoids activate retinoid receptors in the skin leading to clinical improvement in wrinkles, dyspigmentation and skin roughness and are considered to be the mainstay of therapy for photoaged skin. Natural and synthetic topical retinoids are reviewed with respect to their molecular mechanisms and clinical effects.
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