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Cosmeceuticals, defined for the purpose of this chapter as highly efficacious functional ingredients or final products, are becoming more commonplace in the skincare market globally, in particular within the anti-aging category. Many of these ingredients or products aim to improve the clinical features of photoaged skin such as wrinkles and pigmentation through targeting the underlying causes of these clinical features, with increasingly comprehensive efficacy and mechanistic data to support these claims. In this chapter, we review the main classes of cosmeceuticals, the biological endpoints they target together with the evidence that supports their clinical efficacy.

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