CHAPTER 28: Heavy Metals II (Arsenic, Chromium, Nickel, Vanadium) and Micronuclei

Different studies have demonstrated the in vitro/in vivo genotoxicity of different metals by using the micronucleus (MN) assay in different cell types and organisms, including humans. In this chapter, we summarize the data obtained when arsenic, chromium, nickel, and vanadium were evaluated using the MN assay. For each one of the selected metals, the obtained information has been categorized according to whether it was obtained using in vitro or in vivo approaches. In vivo data has also been classified taking into account if it was obtained from biomonitoring studies involving human exposed populations, or from other in vivo models.