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New Developments in Mass Spectrometry
Lipidomics: Current and Emerging Techniques
Edited by
William Griffiths;
William Griffiths
Swansea University, UK
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Yuqin Wang
Yuqin Wang
Swansea University, UK
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Hardback ISBN:
978-1-78801-160-0
PDF ISBN:
978-1-78801-310-9
EPUB ISBN:
978-1-83916-092-9
Special Collection:
2020 ebook collection
No. of Pages:
288
Published online:
13 Jan 2020
Published in print:
23 Jan 2020
Book Chapter
CHAPTER 3: Low-flow Rate Separations of Lipids
By
Steven Ray Wilson
Steven Ray Wilson
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Published:13 Jan 2020
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Special Collection: 2020 ebook collection
Page range:
49 - 73
Citation
H. Roberg-Larsen and S. R. Wilson, in Lipidomics: Current and Emerging Techniques, ed. W. Griffiths and Y. Wang, The Royal Society of Chemistry, 2020, pp. 49-73.
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Low-flow rate separation systems (e.g. nano liquid chromatography and capillary electrophoresis) can allow for enhanced sensitivity and/or resolution. Such systems can be used for detecting low-abundant lipids, performing lipidomics of very small amounts of sample, and for studying interactions between lipids and other compounds, e.g. drugs. Low-flow separation systems are highly compatible with mass spectrometry, on-line sample preparation, and multi-dimensional chromatography, for example.
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