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Chemical Biology
Synthetic Glycomes
Edited by
Peng George Wang
Peng George Wang
Georgia State University , USA
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Hardback ISBN:
978-1-78801-164-8
PDF ISBN:
978-1-78801-657-5
EPUB ISBN:
978-1-78801-777-0
Special Collection:
2019 ebook collection
Series:
Chemical Biology
No. of Pages:
469
Publication date:
08 Apr 2019
Book Chapter
CHAPTER 3: Synthetically Useful Glycosyltransferases for the Access of Mammalian Glycomes
By
Garrett A. Edmunds
;
Garrett A. Edmunds
Department of Chemistry, Georgia State University
Atlanta
GA 30303
USA
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Zhigang Wu
;
Zhigang Wu
College of Bioscience and Bioengineering, Hebei University of Science and Technology
Shijiazhuang
Hebei 050018
China
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Lei Li
Lei Li
Department of Chemistry, Georgia State University
Atlanta
GA 30303
USA
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Published:08 Apr 2019
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Special Collection: 2019 ebook collectionSeries: Chemical Biology
Citation
W. Guan, G. A. Edmunds, Z. Wu, and L. Li, in Synthetic Glycomes, ed. W. Guan, L. Li, and P. G. Wang, The Royal Society of Chemistry, 2019, pp. 46-82.
Download citation file:
Glycans play key roles in biological processes. However, complex glycans are not easily accessible and affordable to support diverse functional study. In the efforts of glycan syntheses, one of the most practical approaches is the strategy that employs glycosyltransferases (GTs) – the natural catalysts for glycan biosynthesis. This chapter summarizes the synthetically useful bacterial and mammalian GTs for the preparation of glycans, with an emphasis on mammalian glycans.
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