CHAPTER 15: Bioactivities and Mechanisms of Egg Protein-derived Peptides
Published:01 May 2019
Food protein-derived bioactive peptides have gained substantial interest during recent decades owing to their potential in modulating various physiological functions. As a high-quality, affordable and universally accepted protein source, egg is an ideal candidate for identification of numerous bioactive peptides. Extensive research has been carried out on identification and activity characterization of antihypertensive peptides, antidiabetic peptides, anticancer peptides, immunomodulatory peptides and antioxidant peptides. Mechanistic study of egg protein-derived bioactive peptides revealed the complexity of actions of these peptides as they may play multiple roles in regulating physiological functions, which warrants further investigation. The objectives of this book chapter are to summarize recent research progress on egg peptides and to identify the research gaps to translate the laboratory research into real-world applications of egg peptides as functional foods and nutraceuticals. Future research is expected to establish biologically relevant methods to replace chemical-based activity assay, to establish the efficacy and safety of egg peptides in human trials, to characterize peptide and cell cross-talks, to explore the multi-bioactivity of egg peptides, and to study the interactions between egg peptides and gut microbiota.