Chapter 21: Very Fast MAS NMR >60 kHz for Structural Elucidation

Recent progress of fast MAS technology drives diverse methodological developments of solid-state NMR and applications to various systems including polymer, pharmaceutical compounds, biological molecules, etc. Fast MAS is beneficial to systems with large anisotropies and spin networks with intense homonuclear interactions. In addition, the small rotor size associated with the fast MAS probe allows the analysis of volume limited samples. First, fast MAS application to large anisotropies which MAS averages out is presented. Then, ¹H NMR at very fast MAS rate is discussed. High-resolution ¹H NMR, ¹H/¹H homonuclear correlation, ¹H–¹H distance measurements, ¹H chemical shift anisotropy determination and indirect detection of insensitive nuclei are introduced.