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While continuous-flow organic synthesis attracts considerable attention in chemical society, there have still been strong demands for more efficient methods for realizing one-flow synthesis of complex molecules by connecting more than two flow reactions directly. Catalytic flow reactions give solutions for such requirements particularly in the case of using fixed bed reactors with heterogeneous catalysts. In this chapter, recent progress in flow reactions with heterogeneous catalysts is reviewed. Especially, enantioselective reactions, photocatalytic reactions, and integrated multi-step flow reactions are focused upon.

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