Skip Nav Destination
Green Chemistry Series
Green Synthetic Processes and Procedures
Edited by
Roberto Ballini
Roberto Ballini
University of Camerino, Italy
Search for other works by this author on:
Hardback ISBN:
978-1-78801-512-7
PDF ISBN:
978-1-78801-613-1
EPUB ISBN:
978-1-78801-839-5
Series:
Green Chemistry
No. of Pages:
413
Published online:
27 Jun 2019
Published in print:
08 Jul 2019
Book Chapter
CHAPTER 3: Application of Step, Cumulative, and Global E-factor and Process Mass Intensity Metrics to Gauge Synthesis Efficiency: l-DOPA and Apixaban Pharmaceutical Examples
By
John Andraos
John Andraos
Search for other works by this author on:
-
Published:27 Jun 2019
-
Series: Green Chemistry
Page range:
39 - 52
Citation
J. Andraos, in Green Synthetic Processes and Procedures, ed. R. Ballini, The Royal Society of Chemistry, 2019, pp. 39-52.
Download citation file:
The utility of step, cumulative, and global E-factor and process mass intensity metrics is demonstrated for the analysis of the material efficiency of synthesis plans for the pharmaceuticals l-DOPA and apixaban. The mathematical relationships relating global and cumulative metrics to step metrics are applicable to any synthesis plan for any molecule.
You do not currently have access to this chapter, but see below options to check access via your institution or sign in to purchase.
Digital access
$64.60
