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Drug Discovery
Antiviral Discovery for Highly Pathogenic Emerging Viruses
Edited by
César Muñoz-Fontela;
César Muñoz-Fontela
Bernhard Nocht Institute for Tropical Medicine, Germany
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Rafael Delgado
Rafael Delgado
Hospital Universitario 12 de Octubre, Madrid, Spain
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Hardback ISBN:
978-1-78801-564-6
PDF ISBN:
978-1-78801-685-8
EPUB ISBN:
978-1-83916-053-0
Special Collection:
2021 ebook collection
Series:
Drug Discovery
No. of Pages:
290
Publication date:
26 Nov 2021
Book Chapter
Chapter 5: Antiviral Strategies for Ebola Virus and Other Filoviruses: Antibodies
By
Larry Zeitlin
Mapp Biopharmaceutical, Inc. 4921 Directors Place Suite 100 San Diego CA 92121 USA larry.zeitlin@mappbio.com
Larry Zeitlin
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Marc-Antoine de La Vega
Université Laval, Département de microbiologie-infectiologie et d'immunologie, Faculté de médecine 2325, Rue de l'Université Québec City (Québec) G1V 0A6 Canada gary.pignac-kobinger.1@ulaval.ca
Marc-Antoine de La Vega
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Andrew Hiatt
Mapp Biopharmaceutical, Inc. 4921 Directors Place Suite 100 San Diego CA 92121 USA larry.zeitlin@mappbio.com
Andrew Hiatt
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Gary Kobinger
Université Laval, Département de microbiologie-infectiologie et d'immunologie, Faculté de médecine 2325, Rue de l'Université Québec City (Québec) G1V 0A6 Canada gary.pignac-kobinger.1@ulaval.ca
Gary Kobinger
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Published:26 Nov 2021
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Special Collection: 2021 ebook collectionSeries: Drug Discovery
Citation
Larry Zeitlin, Marc-Antoine de La Vega, Andrew Hiatt, Gary Kobinger, 2021. "Antiviral Strategies for Ebola Virus and Other Filoviruses: Antibodies", Antiviral Discovery for Highly Pathogenic Emerging Viruses, César Muñoz-Fontela, Rafael Delgado
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Antibodies play a critical role in the prevention and resolution of infectious diseases. This chapter focuses on the role of antibodies in filovirus infection and disease. Anti-filovirus antibodies are critical in overcoming filovirus infections as well as in the activity of experimental vaccines. Additionally, antibodies, specifically monoclonal antibodies, show great promise as therapeutic medical countermeasures for filovirus infection.
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