Supramolecular Protein Chemistry: Assembly, Architecture and Application
Building on decades of “host-guest” research, recent years have seen a surge of activity in water-soluble supramolecular receptors for protein recognition and assembly. Progress has been particularly rich in the area of calixarenes, cucurbiturils and molecular tweezers. Emerging applications include controlled protein assembly in solution, crystal engineering, supramolecular control of catalysis (both in vitro and in vivo), as well as novel mechanisms of protein-interaction inhibition with relevance to amyloids and disease. One challenge at the interface of supramolecular chemistry and protein science is to increase interaction and collaboration between chemists and biochemists/structural biologists.This book addresses the exciting interface of supramolecular chemistry and protein science. Chapters cover supramolecular approaches to protein recognition, assembly and regulation. Principles outlined will highlight the opportunities that are readily accessible to collaborating chemists and biochemists, enriching the breadth and scope of this multidisciplinary field. Supramolecular Protein Chemistry will be of particular interest to graduate students and researchers working in supramolecular chemistry, protein science, self-assembly, biomaterials, biomedicine and biotechnology.
Supramolecular Protein Chemistry: Assembly, Architecture and Application, The Royal Society of Chemistry, 2020.
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Table of contents
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Supramolecular Approaches to Protein Recognitionp1-25ByJoseph W. Meisel;Joseph W. MeiselDepartment of Chemistry, New York University100 Washington Square EastNew YorkNY 10012USA[email protected]Department of Chemistry, The George Washington University800 22nd Street NWWashingtonDC 20052USASearch for other works by this author on:Andrew D. HamiltonAndrew D. HamiltonDepartment of Chemistry, New York University100 Washington Square EastNew YorkNY 10012USA[email protected]Search for other works by this author on:
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CHAPTER 2: Macrocycles for Recognition and Sensing of Histone Modificationsp26-61ByRichard J. HooleyRichard J. HooleySearch for other works by this author on:
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CHAPTER 3: Sequence Predictive Recognition of Proteins and Peptides by Synthetic and Natural Receptorsp62-103ByAdam R. UrbachAdam R. UrbachSearch for other works by this author on:
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CHAPTER 4: Protein Modulation by Cucurbiturilsp104-123ByTim Wezeman;Tim WezemanLaboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of TechnologyDen Dolech 25612AZEindhovenThe Netherlands[email protected]Search for other works by this author on:Pim J. De Vink;Pim J. De VinkLaboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of TechnologyDen Dolech 25612AZEindhovenThe Netherlands[email protected]Search for other works by this author on:Luc BrunsveldLuc BrunsveldLaboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of TechnologyDen Dolech 25612AZEindhovenThe Netherlands[email protected]Search for other works by this author on:
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CHAPTER 5: Supramolecular Nanoassemblies Based on Proteins and Cyclodextrin Derivativesp124-160ByYing-Ming Zhang;Ying-Ming ZhangCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai UniversityTianjin 300071China[email protected]Search for other works by this author on:Yao-Hua Liu;Yao-Hua LiuCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai UniversityTianjin 300071China[email protected]Search for other works by this author on:Yu LiuYu LiuCollege of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai UniversityTianjin 300071China[email protected]Search for other works by this author on:
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CHAPTER 6: Molecular Tweezers and Clips that Modify Protein Functionp161-198ByThomas SchraderThomas SchraderSearch for other works by this author on:
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CHAPTER 7: Molecular Glues for Protein Assemblyp199-232ByPeter B. CrowleyPeter B. CrowleySearch for other works by this author on:
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CHAPTER 8: The Inducing Ligand Strategy for Supramolecular Protein Assemblyp233-257ByRongting Hu;Rongting HuThe State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan UniversityShanghai 200438PR China[email protected]Search for other works by this author on:Guang Yang;Guang YangBiomass Molecular Engineering Center and Department of Materials Science and Engineering, School of Forestry and Landscape Architecture, Anhui Agricultural UniversityHefei, Anhui 230036ChinaSearch for other works by this author on:Guosong ChenGuosong ChenThe State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Fudan UniversityShanghai 200438PR China[email protected]Search for other works by this author on:
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CHAPTER 9: Functional Protein–(Bio)Polymer Assembliesp258-306BySeah Ling Kuan;Seah Ling KuanMax-Planck Institute for Polymer ResearchAckermannweg 1055128 MainzGermany[email protected][email protected]Institute of Inorganic Chemistry I, Ulm UniversityAlbert-Einstein-Allee 1189081 UlmGermanySearch for other works by this author on:Fernando R. G. Bergamini;Fernando R. G. BergaminiInstitute of Chemistry, Federal University of UberlândiaJoão Naves de Ávila Avenue, 2121Santa Mônica, UberlândiaMGBrazilSearch for other works by this author on:Tanja WeilTanja WeilMax-Planck Institute for Polymer ResearchAckermannweg 1055128 MainzGermany[email protected][email protected]Institute of Inorganic Chemistry I, Ulm UniversityAlbert-Einstein-Allee 1189081 UlmGermanySearch for other works by this author on:
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