CHAPTER 8: The Inducing Ligand Strategy for Supramolecular Protein Assembly

This chapter focuses on supramolecular protein assemblies driven by the inducing ligand strategy, which was proposed by our group some years ago. The background to this strategy, the first example of a protein crystalline framework, and various extensions will be discussed. With the inducing ligand strategy it is possible to construct large-scale, well-ordered protein assemblies ranging from one-dimensional fibres to two-dimensional nanosheets and three-dimensional protein crystals. The comprehensive characterization of these nanostructures by various techniques will be described. The purpose of this chapter is to emphasize the importance of the highly interdisciplinary field of supramolecular protein assembly and to promote its application in various fields, especially in biology.