Soft Matter for Biomedical Applications
Chapter 10: Minimalistic Peptide Self-assembly into Supramolecular Biomaterials
Published:07 Jun 2021
M. C. Cringoli, P. Fornasiero, S. Marchesan, 2021. "Minimalistic Peptide Self-assembly into Supramolecular Biomaterials", Soft Matter for Biomedical Applications, Helena S Azevedo, João F Mano, João Borges
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Over the past 30 years, peptide-based supramolecular materials have been used in a wide range of biomedical applications, from immunotherapy and drug delivery vehicles, to the development of theranostic tools and scaffolds for tissue engineering, for which they have very high potential (see Figure 10.1).1,2 They are considered prominent biomaterials thanks to their unique functional properties and their similarity to biological structures that are self-assembled and highly ordered(e.g., enzymes, transmembrane receptors, microtubules, antibodies, hormones), which characterize all living systems in nature.3 Peptide self-assembly is driven by local non-covalent interactions between peptide molecules under thermodynamic and...