Soft Matter for Biomedical Applications
Chapter 26: Animal Protein-based Soft Materials for Tissue Engineering Applications
Published:07 Jun 2021
C. A. Custódio, S. C. Santos, C. F. Monteiro, I. A. Deus, M. C. Gomes, J. F. Mano, 2021. "Animal Protein-based Soft Materials for Tissue Engineering Applications", Soft Matter for Biomedical Applications, Helena S Azevedo, João F Mano, João Borges
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Typically, biomedical applications involve the integration of an engineered material within a living organism.
The success of a biomedical device is highly dependent on the material used, which should be noncytotoxic, nonimmunogenic and minimally proinflammatory.1,2 Ranging from synthetic to natural polymers, countless materials have been reported for biomedical use.3,4
The extracellular matrix (ECM) is the natural 3D microenvironment in which cells reside. It is a dynamic and complex milieu, composed of multiple proteins, glycosaminoglycans and soluble factors. Accordingly, the ECM, its components, and more particularly proteins, are highly interesting for soft materials design and fabrication, especially when aiming...