Droplet Microfluidics
Droplet microfluidics offers tremendous potential as an enabling technology for high-throughput screening. It promises to yield novel techniques for personalised medicine, drug discovery, disease diagnosis, establishing chemical libraries, and the discovery of new materials. Despite the enormous potential to contribute to a broad range of applications, the expected adoption has not yet been seen, partly due to the interdisciplinary nature and the fact that, up until now, information has been scattered across the literature. This book goes a long way to addressing these issues.
Edited by two leaders, this book has drawn together expertise from around the globe to form a unified, cohesive resource for the droplet microfluidics community. Starting with the basic theory of droplet microfluidics before introducing its use as a tool, the reader will be treated to chapters on important techniques, including robust passive and active droplet manipulations and applications such as single cell analysis, which is key for drug discovery. This book is a go-to resource for the community yearning to adopt and promote droplet microfluidics into different applications and will interest researchers and practitioners working across chemistry, biology, physics, materials science, micro- and nano-technology, and engineering.
Droplet Microfluidics, The Royal Society of Chemistry, 2020.
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Table of contents
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CHAPTER 1: History and Current Status of Droplet Microfluidicsp1-14ByC. Ren;C. RenDepartment of Mechanical and Mechatronics Engineering, University of Waterloo 200 University Avenue WestWaterlooOntarioCanada N2L 3G1[email protected]Search for other works by this author on:A. LeeA. LeeDepartment of Biomedical Engineering, University of California IrvineIrvineCA 92697-2715USASearch for other works by this author on:
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CHAPTER 2: Fundamentalsp15-44ByN. QinN. QinUniversity of Waterloo, Department of Mechanical and Mechatronics Engineering200 University Avenue WestWaterlooOntarioCanada N2L 3G1[email protected]Search for other works by this author on:
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CHAPTER 3: Technological Development – Droplet as a Toolp45-88ByAdrian J. T. Teo;Adrian J. T. TeoQueensland Micro- and Nanotechnology Centre, Griffith University170 Kessels RoadBrisbaneQLD 4111Australia[email protected]Search for other works by this author on:Say Hwa Tan;Say Hwa TanQueensland Micro- and Nanotechnology Centre, Griffith University170 Kessels RoadBrisbaneQLD 4111Australia[email protected]Search for other works by this author on:Nam-Trung NguyenNam-Trung NguyenQueensland Micro- and Nanotechnology Centre, Griffith University170 Kessels RoadBrisbaneQLD 4111Australia[email protected]Search for other works by this author on:
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CHAPTER 4: Droplet Gene Analysis – Digital PCRp89-121ByEmilis Gegevicius;Emilis GegeviciusInstitute of Biotechnology, Vilnius UniversitySauletekio avenue 7LT-02571 VilniusLithuaniaSearch for other works by this author on:Karolis Goda;Karolis GodaInstitute of Biotechnology, Vilnius UniversitySauletekio avenue 7LT-02571 VilniusLithuaniaSearch for other works by this author on:Linas MazutisLinas MazutisComputational and Systems Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer CenterNew YorkNY 10065USA[email protected]Search for other works by this author on:
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CHAPTER 5: Microfluidic Applications in Single-cell Genomic, Transcriptomic and Proteomic Analysisp122-146ByDavid RuffDavid RuffSearch for other works by this author on:
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CHAPTER 6: The Drop-screen for Biological Functional Assayp147-174ByShih-Chung Wei;Shih-Chung WeiDepartment of Biomedical Engineering, National University of SingaporeSingaporeSearch for other works by this author on:Myat Noe Hsu;Myat Noe HsuDepartment of Biomedical Engineering, National University of SingaporeSingaporeSearch for other works by this author on:Chia-Hung ChenChia-Hung ChenSearch for other works by this author on:
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CHAPTER 7: Application in Single-cell Functional Analysisp175-192ByXiaoming Chen;Xiaoming ChenSue and Bill Gross Stem Cell Research Center, Sue & Bill Gross Hall CIRM Institute, University of California Irvine845 Health Sciences Road, Suite 3027IrvineCA 92697USA[email protected]Department of Pharmaceutical Sciences, University of California IrvineIrvineCA 92697USAChao Family Comprehensive Cancer Center, University of California IrvineIrvineCA 92697USAEdwards Life Sciences Center for Advanced Cardiovascular Technology, University of California IrvineIrvineCA 92697USADepartment of Biomedical Engineering, University of California IrvineIrvineCA 92697USADepartment of Biological Chemistry, University of California IrvineIrvineCA 92697USASearch for other works by this author on:Weian ZhaoWeian ZhaoSue and Bill Gross Stem Cell Research Center, Sue & Bill Gross Hall CIRM Institute, University of California Irvine845 Health Sciences Road, Suite 3027IrvineCA 92697USA[email protected]Department of Pharmaceutical Sciences, University of California IrvineIrvineCA 92697USAChao Family Comprehensive Cancer Center, University of California IrvineIrvineCA 92697USAEdwards Life Sciences Center for Advanced Cardiovascular Technology, University of California IrvineIrvineCA 92697USADepartment of Biomedical Engineering, University of California IrvineIrvineCA 92697USADepartment of Biological Chemistry, University of California IrvineIrvineCA 92697USASearch for other works by this author on:
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CHAPTER 8: Droplet Microfluidics: Applications in Synthetic Biologyp193-222BySamuel R. Little;Samuel R. LittleDepartment of Electrical and Computer Engineering, Concordia UniversityMontréalQCCanadaSearch for other works by this author on:James M. Perry;James M. PerryDepartment of Biology, Concordia UniversityMontréalQCCanadaSearch for other works by this author on:Kenza Samlali;Kenza SamlaliDepartment of Electrical and Computer Engineering, Concordia UniversityMontréalQCCanadaSearch for other works by this author on:Steve C. C. ShihSteve C. C. ShihDepartment of Electrical and Computer Engineering, Concordia UniversityMontréalQCCanadaDepartment of Biology, Concordia UniversityMontréalQCCanadaSearch for other works by this author on:
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CHAPTER 9: Tissue Engineering and Analysis in Droplet Microfluidicsp223-260ByChristopher J. EasleyChristopher J. EasleySearch for other works by this author on:
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CHAPTER 10: Emulsion Drops as Templates for the Fabrication of Microparticles and Capsulesp261-289ByE. AmstadE. AmstadInstitute of Materials, Ecole Polytechnique Fédérale de Lausanne (EPFL)1015 LausanneSwitzerland[email protected]Search for other works by this author on:
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CHAPTER 11: Challenges and Opportunities – Future Directionsp290-293ByM. Gilligan;M. GilliganBlacktrace Holdings Ltd3 Anglian Business ParkRoystonSG8 5TWUKSearch for other works by this author on:A. Lee;A. LeeDepartment of Biomedical Engineering, University of CaliforniaIrvineCA 92697-2715USASearch for other works by this author on:C. RenC. RenUniversity of Waterloo, Department of Mechanical and Mechatronics Engineering, 200 University Avenue WestWaterlooOntarioCanada N2L 3G1[email protected]Search for other works by this author on:
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